JACC Cardio Imag:中度瓣膜反流患者或无需频繁超声心动图检查

2014-12-16 高晓方 译 医学论坛网

美国一项研究表明,在心功能稳定的中度主动脉瓣反流(AR)和二尖瓣反流(MR)患者中,频繁超声心动图检查可能并非必需;重度反流患者的左室功能恶化率与病因无关。论文12月10日在线发表于《美国心脏病学会杂志·心血管成像》(JACC Cardiovasc Imaging)。 此项观察性队列研究共纳入130例无症状中重度MR患者和130例无症状中重度AR缓和,并依据年龄和回流量指数对其加以配对。

美国一项研究表明,在心功能稳定的中度主动脉瓣反流(AR)和二尖瓣反流(MR)患者中,频繁超声心动图检查可能并非必需;重度反流患者的左室功能恶化率与病因无关。论文12月10日在线发表于《美国心脏病学会杂志·心血管成像》(JACC Cardiovasc Imaging)。

此项观察性队列研究共纳入130例无症状中重度MR患者和130例无症状中重度AR缓和,并依据年龄和回流量指数对其加以配对。利用定量多普勒确定反流严重度,并以回流量指数≥30 ml/m2定义重度反流。所有患者均接受年度超声心动图随访。

资料图

结果显示,随访期间无论病因如何,重度反流患者均表现为左室容积指数升高和射血分数降低。在中度反流患者中,左室容积和射血分数则无显著变化。重度反流患者在随访期间出现相似的收缩性降低,并且独立于反流病因。在中度反流患者中收缩性参数未出现显著变化。

原始出处:

Kenya Kusunose, Paul C. Cremer, Rayji S. Tsutsui, Richard A. Grimm, James D. Thomas, Brian P. Griffin, Zoran B. Popović.Regurgitant Volume Informs Rate of Progressive Cardiac Dysfunction in Asymptomatic Patients With Chronic Aortic or Mitral Regurgitation.JACC: Cardiovascular Imaging Available online 1 November 2014.doi:10.1016/j.jcmg.2014.09.017


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    2015-05-13 hbwxf
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    2014-12-18 feifers
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