J Am Heart Assoc:钙补充剂的使用可增加冠状动脉钙化的发病风险

2016-10-15 MedSci MedSci原创

最近的随机数据表明,钙补充剂或可增加心血管疾病(CVD)事件的发生风险。在此纵向队列研究中,我们评估了从食物和补充剂中所获得的钙的摄入量与冠状动脉钙化(CAC)之间的关系。研究共纳入了来自动脉粥样硬化多种族研究的5448名非CVD(52%为女性;年龄在45-84岁)患者。评估基线时期研究对象从食物(使用食物频率问卷)和钙补充剂(药物库存)中获得的钙的总摄入量,根据摄入量划分为5个等级。使用CT测量

最近的随机数据表明,钙补充剂或可增加心血管疾病(CVD)事件的发生风险。在此纵向队列研究中,我们评估了从食物和补充剂中所获得的钙的摄入量与冠状动脉钙化(CAC)之间的关系。

研究共纳入了来自动脉粥样硬化多种族研究的5448名非CVD(52%为女性;年龄在45-84岁)患者。评估基线时期研究对象从食物(使用食物频率问卷)和钙补充剂(药物库存)中获得的钙的总摄入量,根据摄入量划分为5个等级。使用CT测量基线时期研究对象的CAC 情况,并在2742参与者(≈10年后)中重复测量CAC。

结果,基线时,平均钙摄入量的5个等级分别为313.3,540.3,783,1168.9,和2157.4毫克/天。女性的钙摄入量较男性高。校正潜在的混杂因素后,1567名基线时期无CAC的研究对象中,根据摄入量1-5等级,10年后发生CAC的相对风险(RR)分别为1(参考),0.95(0.79-1.14),1.02(0.85-1.23),0.86(0.69-1.05),和0.73(0.57-0.93)。计算完总的钙摄入量后,钙补充剂的使用与CAC的发生风险增加相关(RR = 1.22,[1.07-1.39 ])。基线时期CAC>0的参与者中,基线时期的钙摄入量与10年后发生CAC的风险之间无关。

总而言之,通过长期的随访发现,在未使用钙补充剂的情况下,较高的钙摄入量高与CAC较低的发生风险相关,但是在使用了钙补充剂后则可增加CAC的发生风险。

原始出处:

Anderson JJ, et al. Calcium Intake From Diet and Supplements and the Risk of Coronary Artery Calcification and its Progression Among Older Adults: 10‐Year Follow‐up of the Multi‐Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc. 2016;doi:10.1161/JAHA.116.003815.

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    2016-10-21 1e0ba702m86(暂无匿称)

    视频很好,值得反复学习

    0

  4. 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attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-21 大爰

    学习并分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-19 为你把脉

    ccvgghhhh

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-18 为你把脉

    gghhhhhh

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-18 大爰

    学习并分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-18 邓启付

    个人感觉无直接关系,所以无法评估

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Oct 21 08:58:43 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149656, encodeId=e25e149656ef, content=ccvgghhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Wed Oct 19 07:56:27 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149462, encodeId=cbe514946287, content=gghhhhhh, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Tue Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-18 1de8ed50m80(暂无匿称)

    意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1973500, encodeId=264419e350017, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Wed Jun 14 08:35:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663259, encodeId=d3091663259c2, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 22 21:35:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150183, encodeId=2f4915018347, content=视频很好,值得反复学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160717/IMG578BA7C21F5227685.jpg, createdBy=70421925809, createdName=1e0ba702m86(暂无匿称), createdTime=Fri Oct 21 20:46:03 CST 2016, time=2016-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150065, encodeId=fc04150065cf, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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Oct 18 10:43:24 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149386, encodeId=f4661493864f, content=学习并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Tue Oct 18 07:29:08 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149376, encodeId=42601493e607, content=个人感觉无直接关系,所以无法评估, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Oct 18 07:10:39 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149347, encodeId=79f914934ede, content=意思是补充钙的摄入量可以预防冠状动脉钙化,但补充过多的钙剂反而适得其反。, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87421705485, createdName=1de8ed50m80(暂无匿称), createdTime=Tue Oct 18 00:43:28 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149060, encodeId=fed914906013, content=非常好, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Mon Oct 17 18:06:11 CST 2016, time=2016-10-17, status=1, ipAttribution=)]
    2016-10-17 幸运8355

    非常好

    0