J Cell Physiol:多吃番茄可抵抗胃癌的发生

2017-08-02 MedSci MedSci原创

胃癌是一种弥漫性和侵袭性的肿瘤,其死亡率在全世界高居榜首。胃癌发生的易感因素是E-cadherin基因突变、幽门螺杆菌感染和食用过多含盐和烟熏的食物,而新鲜水果和蔬菜的摄入量却很低。在这里,研究人员分析了意大利南部的两种番茄品种(San Marzano和Corbarino)中的总脂溶性提取物对体外胃癌模型(YCC-1,YCC-2和 YCC-3细胞株,侵袭性不同)的影响。结果显示,这两个品种的番茄都

胃癌是一种弥漫性和侵袭性的肿瘤,其死亡率在全世界高居榜首。胃癌发生的易感因素是E-cadherin基因突变、幽门螺杆菌感染和食用过多含盐和烟熏的食物,而新鲜水果和蔬菜的摄入量却很低。在这里,研究人员分析了意大利南部的两种番茄品种(San Marzano和Corbarino)中的总脂溶性提取物对体外胃癌模型(YCC-1,YCC-2和 YCC-3细胞株,侵袭性不同)的影响。

结果显示,这两个品种的番茄都表现出类似的抗肿瘤特性。使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。研究人员发现,番茄提取物对胃癌细胞系的周期进程和凋亡调节都有影响。然而,番茄提取物的抗肿瘤作用的程度似乎与两个番茄品种中类胡萝卜素的含量及其抗氧化活性无关。

总而言之,该研究结果表明,摄入San Marzano和Corbarino或可作为癌症预防的营养支持饮食,同时也可作为癌症患者的抗癌饮食。

原始出处:

Barone D, Cito L, et al., Antitumoral potential, antioxidant activity and carotenoid content of two Southern Italy tomatocultivars extracts: San Marzano and Corbarino. J Cell Physiol. 2017 May 10. doi: 10.1002/jcp.25995.
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    2017-10-18 hittouch
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    2017-10-28 维他命
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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
  5. 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07:17:31 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229616, encodeId=b643229616ab, content=使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Thu Aug 03 16:36:10 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229529, encodeId=8e4822952993, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu Aug 03 11:33:24 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-06 187清风

    多吃新鲜蔬菜水果

    0

  6. 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07:17:31 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229616, encodeId=b643229616ab, content=使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Thu Aug 03 16:36:10 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229529, encodeId=8e4822952993, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu Aug 03 11:33:24 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-05 yfjms

    学习了

    0

  7. 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07:17:31 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229616, encodeId=b643229616ab, content=使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Thu Aug 03 16:36:10 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229529, encodeId=8e4822952993, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu Aug 03 11:33:24 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-03 随梦飞扬

    使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。

    0

  8. 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07:17:31 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229616, encodeId=b643229616ab, content=使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Thu Aug 03 16:36:10 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229529, encodeId=8e4822952993, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu Aug 03 11:33:24 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-03 往日如昨

    学习了谢谢分享

    0

  9. 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07:17:31 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229616, encodeId=b643229616ab, content=使用番茄提取物处理这三种癌细胞可影响癌细胞的粘附和生长,降低细胞的迁移能力。对于非肿瘤细胞,番茄提取物则并无毒性。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Thu Aug 03 16:36:10 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229529, encodeId=8e4822952993, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu Aug 03 11:33:24 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-03 186****0580(小山羊)

    学习了谢谢了。

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229507, encodeId=e89f22950e9e, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Aug 03 10:09:14 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229410, encodeId=357922941040, content=多吃番茄好多好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu Aug 03 06:22:00 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-03 半夏微凉

    多吃番茄好多好处

    0

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