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PLoS One：坚果改善T2DM患者血糖

2014-08-20 cath 编译 医学论坛网

木本坚果2型糖尿病患者血糖
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既往研究显示，木本坚果与糖尿病风险减少有关，但与血糖有关的随机研究结论尚不一致。为糖尿病指南进展提供更好地证据，加拿大学者们进行了一项随机对照试验的系统回顾和荟萃分析，以评估市场上的木本坚果对糖尿病人群血糖的影响。结果表明，木本坚果有助改善2型糖尿病患者血糖。研究论文7月30日发表于《公共科学图书馆·综合》杂志。[pdf free]  研究者们检索了MEDLINE、 EMBASE、CIN

既往研究显示，木本坚果与糖尿病风险减少有关，但与血糖有关的随机研究结论尚不一致。为糖尿病指南进展提供更好地证据，加拿大学者们进行了一项随机对照试验的系统回顾和荟萃分析，以评估市场上的木本坚果对糖尿病人群血糖的影响。结果表明，木本坚果有助改善2型糖尿病患者血糖。研究论文7月30日发表于《公共科学图书馆·综合》杂志。[pdf free]  

研究者们检索了MEDLINE、 EMBASE、CINAHL和Cochrane数据库中至2014年4月6日的为期≥3周的随机对照试验，这些试验均对比了患者摄入等热量的木本坚果和未摄入坚果对糖化血红蛋白(HbA1c)、空腹血糖和胰岛素以及胰岛素抵抗的影响。

结果显示，共纳入12项试验(n = 450)。与对照饮食相比，饮食摄入中等剂量木本坚果(56 g/d)可显著降低HbA1c(P = 0.0003)和空腹血糖(P = 0.03)。在研究中，他们观察到对空腹胰岛素和胰岛素抵抗而言，木本坚果无显著治疗作用。

原始出处：


Viguiliouk E1, Kendall CW2, Blanco Mejia S1, Cozma AI1, Ha V1, Mirrahimi A3, Jayalath VH4, Augustin LS1, Chiavaroli L1, Leiter LA5, de Souza RJ6, Jenkins DJ5, Sievenpiper JL7.Effect of tree nuts on glycemic control in diabetes: a systematic review and meta-analysis of randomized controlled dietary trials.PLoS One. 2014 Jul 30;9(7):e103376. doi: 10.1371/journal.pone.0103376. eCollection 2014. [pdf free]       

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1717725, encodeId=e3fe1e17725ce, content=<a href='/topic/show?id=f6b01e050d5' target=_blank style='color:#2F92EE;'>#T2DM患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17050, encryptionId=f6b01e050d5, topicName=T2DM患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b70c32458048, createdName=stfoxst, createdTime=Wed Sep 17 11:33:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20633, encodeId=a1bf2063386, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:23:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789614, encodeId=0e5e1e8961411, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Apr 13 20:33:00 CST 2015, time=2015-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11250, encodeId=86261125090, content=再次证明地中海饮食的益处., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=870092288, createdName=rosa00tong, createdTime=Sun Aug 24 17:23:00 CST 2014, time=2014-08-24, status=1, ipAttribution=)]
    2014-09-17 stfoxst

    #T2DM患者#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1717725, encodeId=e3fe1e17725ce, content=<a href='/topic/show?id=f6b01e050d5' target=_blank style='color:#2F92EE;'>#T2DM患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17050, encryptionId=f6b01e050d5, topicName=T2DM患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b70c32458048, createdName=stfoxst, createdTime=Wed Sep 17 11:33:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20633, encodeId=a1bf2063386, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:23:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789614, encodeId=0e5e1e8961411, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Apr 13 20:33:00 CST 2015, time=2015-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11250, encodeId=86261125090, content=再次证明地中海饮食的益处., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=870092288, createdName=rosa00tong, createdTime=Sun Aug 24 17:23:00 CST 2014, time=2014-08-24, status=1, ipAttribution=)]
    2015-04-11 x35042875

    糖尿病肾病进展风险的关系没有发现。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1717725, encodeId=e3fe1e17725ce, content=<a href='/topic/show?id=f6b01e050d5' target=_blank style='color:#2F92EE;'>#T2DM患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17050, encryptionId=f6b01e050d5, topicName=T2DM患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b70c32458048, createdName=stfoxst, createdTime=Wed Sep 17 11:33:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20633, encodeId=a1bf2063386, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:23:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789614, encodeId=0e5e1e8961411, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Apr 13 20:33:00 CST 2015, time=2015-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11250, encodeId=86261125090, content=再次证明地中海饮食的益处., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=870092288, createdName=rosa00tong, createdTime=Sun Aug 24 17:23:00 CST 2014, time=2014-08-24, status=1, ipAttribution=)]
    2015-04-13 119337457

    #Plos one#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1717725, encodeId=e3fe1e17725ce, content=<a href='/topic/show?id=f6b01e050d5' target=_blank style='color:#2F92EE;'>#T2DM患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17050, encryptionId=f6b01e050d5, topicName=T2DM患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b70c32458048, createdName=stfoxst, createdTime=Wed Sep 17 11:33:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20633, encodeId=a1bf2063386, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:23:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789614, encodeId=0e5e1e8961411, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Apr 13 20:33:00 CST 2015, time=2015-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11250, encodeId=86261125090, content=再次证明地中海饮食的益处., beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=870092288, createdName=rosa00tong, createdTime=Sun Aug 24 17:23:00 CST 2014, time=2014-08-24, status=1, ipAttribution=)]
    2014-08-24 rosa00tong

    再次证明地中海饮食的益处.

    0