JACC:ST段抬高的心肌梗死患者接受急诊PCI治疗后的长短期死因

2014-12-01 MedSci译 MedSci原创

背景: 接受急诊经皮冠状动脉介入治疗(PCI)患者的短期死亡率已经被深入的研究,而ST段抬高的心肌梗死(STEMI)患者的长期死因仍是未知。目标:本研究的目的是描述STEMI患者接受急诊PCI的时间和死亡原因之间的关联。方法:一个集中居民登记习题,病人档案,有准确的记录链接的公共疾病和死亡原因的登记资料,被用来跟踪连续2804 名接受急诊PCI治疗的STEMI患者(年龄63±13岁,72%男性)的

背景: 接受急诊经皮冠状动脉介入治疗(PCI)患者的短期死亡率已经被深入的研究,而ST段抬高的心肌梗死STEMI)患者的长期死因仍是未知。

目标:本研究的目的是描述STEMI患者接受急诊PCI的时间和死亡原因之间的关联。

方法:一个集中居民登记习题,病人档案,有准确的记录链接的公共疾病和死亡原因的登记资料,被用来跟踪连续2804 名接受急诊PCI治疗的STEMI患者(年龄63±13岁,72%男性)的时间和死亡原因。

结果:患者随访的中位数为4.7年。期间,共有13447患者年,717例患者死亡。30天内死亡的主要原因是心源性休克和心脏骤停后的缺氧性脑损伤。年龄,血管大小和流量,以及心脏衰竭和糖尿病的存在,是死亡率的独立预测因子。 30天之后的死亡中,年心源性死亡率为<1.5%。超过30天后的死亡的原因65%是非心源性的(主要是恶性肿瘤和肺部疾病)。 30天,1年期和5年期全因(和心的)死亡率分别为7.9%(7.3%),11.4%(8.4%)和23.3%(13.8%)。



结论:患者接受STEMI治疗后的第一个月有一个良好的预后,接下来的心脏性猝死的年风险<1.5%。非心源性原因是这些患者后来死亡的主要原因。

原始出处:

Frants Pedersen, MD, PhD; Vitalij Butrymovich, MD; Henning Kelbæk, MD, DMSc; Kristian Wachtell, MD, PhD; Steffen Helqvist, MD, DMSc; Jens Kastrup, MD, DMSc; Lene Holmvang, MD, DMSc; Peter Clemmensen, MD, DMSc; Thomas Engstrøm, MD, PhD, DMSc; Peer Grande, MD, DMSc; Kari Saunamäki, MD, DMSc; Erik Jørgensen, MD.Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI.
J Am Coll Cardiol. 2014;64(20):2101-2108. doi:10.1016/j.jacc.2014.08.037


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    2015-05-30 slcumt
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    2015-04-21 hbwxf
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    2014-12-03 gdsun
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    2014-12-03 hyf035