JAHA:迷宫手术与二尖瓣手术同时进行后的病窦综合征

2018-10-03 xiangting MedSci原创

无论基础病因是什么,添加 MP后,都应该认识到出现SSS的风险。

这项研究旨在表征二尖瓣手术时添加迷宫手术(MP)以后病窦综合征(SSS)的出现。

对750例患者的随访数据进行了分析(中位数,3.6年),其中风湿病的患病率为57.6%。35例患者发生了SSS,并随时间增加:术后1年、2年和4年的发病率分别为2.9%、3.7%和4.3%。添加MP后出现SSS(风险比,7.44; 95%置信区间,3.45-16.05; P<0.001)和植入起搏器的风险更高(风险比,3.61; 95%置信区间,1.95-6.67; P<0.001)。出现SSS的患者4年临床事件发生率较高(死亡、卒中和住院)(67.5±8.5% vs 33.0±1.9%; P<0.001)。调整年龄和术前收缩期肺动脉压峰值后,病变范围(双房vs左心房MP)与出现SSS独立相关(风险比,3.58; 95%置信区间,1.08-11.86; P=0.037),而不是基础病因(风湿性vs非风湿性)。双房MP的不良影响在轻度术前三尖瓣返流患者中得到证实,其SSS的发病率较高(4.6±1.4%vs 1.0±0.7%; P=0.023),而不是中至重度三尖瓣返流患者(6.8±1.7% vs 3.8±3.8%; P=0.337)。房颤的复发与MP的病变范围无关。

无论基础病因是什么,添加 MP后,都应该认识到出现SSS的风险。考虑到双侧MP的附加风险和相似的房颤复发率,有必要最小化病变范围。

原始出处:

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    2018-10-05 wwzzly
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  5. 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time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-05 zhaohui6731
  6. 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time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-04 一天没事干

    很好的学习机会

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=347864, encodeId=d5f534e86463, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:27 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347863, encodeId=426834e863de, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:15 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-04 龙胆草

    学习谢谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1952154, encodeId=3a8b1952154d7, content=<a href='/topic/show?id=f11b2390577' target=_blank style='color:#2F92EE;'>#二尖瓣手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23905, encryptionId=f11b2390577, topicName=二尖瓣手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5a6b240, createdName=俅侠, createdTime=Fri Aug 16 23:30:00 CST 2019, time=2019-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1814206, encodeId=e71d181420642, content=<a href='/topic/show?id=b48494621d1' target=_blank style='color:#2F92EE;'>#迷宫手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94621, encryptionId=b48494621d1, topicName=迷宫手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7460166, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu Oct 04 20:15:42 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347876, encodeId=3c7734e8761f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Oct 04 09:22:25 CST 2018, time=2018-10-04, status=1, ipAttribution=), 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time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-04 Y—xianghai

    学习了长知识

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu Oct 04 20:15:42 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347876, encodeId=3c7734e8761f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Oct 04 09:22:25 CST 2018, time=2018-10-04, status=1, ipAttribution=), 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time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-04 Y—xianghai

    学习了长知识

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Thu Oct 04 20:15:42 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347876, encodeId=3c7734e8761f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Oct 04 09:22:25 CST 2018, time=2018-10-04, status=1, ipAttribution=), 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time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347862, encodeId=075234e862b7, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Oct 04 07:12:10 CST 2018, time=2018-10-04, status=1, ipAttribution=)]
    2018-10-04 Y—xianghai

    学习了长知识

    0

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