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婴儿接受麻醉会影响智商吗？

2016-09-10 佚名 爱唯医学网

婴儿麻醉
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费城儿童医院的研究人员对左心发育不良综合征的新生儿之研究报道，每年约10,000例新生儿因先天性心脏缺陷而接受全身麻醉，他们吸入越多的麻醉药，对其神经系统发展的影响将更大。此前研究认为患者神经发育不良与早产和遗传相关，Laura K. Diaz及其同事首次对婴儿心脏手术中，神经发育结果和可改变因素之一致性关系进行研究。该研究入组96例左心发育不良综合征（HLHS）或类似综合征的患者，这些患者于19

费城儿童医院的研究人员对左心发育不良综合征的新生儿之研究报道，每年约10,000例新生儿因先天性心脏缺陷而接受全身麻醉，他们吸入越多的麻醉药，对其神经系统发展的影响将更大。


此前研究认为患者神经发育不良与早产和遗传相关，Laura K. Diaz及其同事首次对婴儿心脏手术中，神经发育结果和可改变因素之一致性关系进行研究。


该研究入组96例左心发育不良综合征（HLHS）或类似综合征的患者，这些患者于1998至2003年期间使用了挥发性麻醉药（VAA）。患者接受一系列针对4-5岁的神经发育测试，包括全面智商（FSIQ）、言语智商（VIQ）、操作智商（PIQ）和处理速度。


这项研究表明，接受阶段性重建手术的HLHS儿童患者，从婴儿期开始使用的挥发性麻醉药越多，全面智商和言语智商的表现越差，该结果提示挥发性麻醉药的使用可能是不良神经发育结果的危险因素。


近年来，左心发育不良综合征新生儿的生存率显著提高，医师开始担心这些孩子后续遇到神经发育不良的问题。Diaz博士及其同事们承认，先前研究表明，如心肺流转术和住院时间，可能会影响孩子的神经发育，但结果不一致。反之，对于曾接受心脏手术的患者，患者的个体因素，如出生体重、种族和遗传疾病是神经发育的重大决定因素。


Diaz博士说其研究结果仅为初步，并未在实践中获得验证，需透过前瞻性随机对照多中心临床试验，继续阐明早期和重复使用挥发性麻醉药对小儿神经系统发育的影响。

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    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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    2016-09-13 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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    2016-09-13 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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    2016-09-12 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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    2016-09-12 晓辰

    #智商#

    0

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