J Clin Periodontol:牙周基础治疗联合维持期治疗可有效控制局限型侵袭性牙周炎

2017-04-25 MedSci MedSci原创

本研究旨在评估局限型侵袭性牙周炎(LAP)患者对牙周治疗和维持的长期效果。研究共纳入了141名诊断为LAP的非洲裔美国人,年龄为5-25岁。对所有研究对象进行牙周机械清创,并使用阿莫西林/甲硝唑辅助用药1周。机械治疗重复需要和临床参数记录在基线时期,以及治疗后第3、6、12、18和24个月时记录牙周检查大表,此外在治疗后的2年每年随访复查一次,必要时重复进行牙周机械治疗。根据X线片回顾性分析患者的

本研究旨在评估局限型侵袭性牙周炎(LAP)患者对牙周治疗和维持的长期效果。

研究共纳入了141名诊断为LAP的非洲裔美国人,年龄为5-25岁。对所有研究对象进行牙周机械清创,并使用阿莫西林/甲硝唑辅助用药1周。基线时期,以及治疗后第3、6、12、18和24个月时记录牙周检查大表,此外在治疗后的2年每年随访复查一次,必要时重复进行牙周机械治疗。根据X线片回顾性分析患者的乳牙及恒牙列情况,并分析其健康的兄弟姐妹(HS)。

结果发现,牙周机械治疗显著改善了患者的牙周袋探针水平及临床附着水平,且效果可长达4年(分别平均减少:2.18±1.03 mm和2.80±1.43 mm)。所有探诊深度不合格的牙周位点在治疗及复查的阶段均得到改善,且效果可保持长达4年。治疗期间并无任何影响治疗效果的抗生素相关并发症的发生。恒牙列中90%的LAP患者和32%的HS X线检查可见其乳牙列存在骨丢失。

总而言之,该研究发现,机械清创联合1周的全身抗生素用药以及适当的牙周维护可有效治疗LAP,且效果可长达4年。恒牙列出现的LAP或已在其乳牙列时便已存在。

原始出处:

Miller KA, Branco-de-Almeida LS, Wolf S, et al. Long-term clinical response to treatment and maintenance of localized aggressive periodontitis: a cohort study. J Clin Periodontol. 2017 Feb;44(2):158-168. doi: 10.1111/jcpe.12640.


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    2017-12-13 feather89
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    2017-04-27 sunyl07
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