心血管

订阅

MedSci主页 / 所有栏目 / 心血管

ESC 2017：DETO2X-AMI 氧疗并不会改善心脏病症状患者的生存率

2017-08-29 MedSci MedSci原创

关注

DETO2X-AMI是一项前瞻性随机对照研究，共纳入了瑞典35家医院的6229名心脏病症状性的患者。旨在确定当前临床广泛应用的氧疗方案对于疑似急性心梗(AMI)患者是否具有治疗作用。其中一半患者接受面罩吸氧治疗，另外半数患者作为对照。结果显示，随机分组后一年两组患者的死亡率并无明显统计学差异（5.0% VS. 5.1%），同样次级终点（包括心脏病发作或心肌损伤等）也无明显统计学差异。即使是在高风险

DETO2X-AMI是一项前瞻性随机对照研究，共纳入了瑞典35家医院的6229名心脏病症状性的患者。旨在确定当前临床广泛应用的氧疗方案对于疑似急性心梗(AMI)患者是否具有治疗作用。其中一半患者接受面罩吸氧治疗，另外半数患者作为对照。

结果显示，随机分组后一年两组患者的死亡率并无明显统计学差异（5.0% VS. 5.1%），同样次级终点（包括心脏病发作或心肌损伤等）也无明显统计学差异。

即使是在高风险患者中，如吸烟、老年、糖尿病或存在心脏病发作史等，两组患者的死亡率依然无统计学差异。

对于伴有缺氧、含氧量低或心衰的STEMI患者，ESC 指南推荐氧疗。但是在不伴有这些症状的患者中，系统应用氧疗能否使患者受益则尚不确定。目前指南对氧疗的应用推荐变得更加严格，当前针对氧疗的建议还只是基于专家意见，该研究结果将会对未来指南的更新和临床实践的改变产生直接的影响。

DETO2X-AMI试验是首次面向疑似AMI患者的大规模临床随机对照试验，其规模足以揭示氧疗对患者死亡率及发病率的影响。该研究的样本量是所有既往研究患者总数的6倍之多，且患者的范围来源更加广泛，使得其结论也更适用于日常临床实践。

原始出处：

Oxygen therapy does not improve survival in patients with heart attack symptoms (DETO2X-AMI). 28 Aug 2017.

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1256594, encodeId=517c1256594a3, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466537, encodeId=7f4c146653e5f, content=<a href='/topic/show?id=621d6402097' target=_blank style='color:#2F92EE;'>#氧疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64020, encryptionId=621d6402097, topicName=氧疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8a786841989, createdName=rgjl, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238398, encodeId=3ffd23839835, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 29 19:44:06 CST 2017, time=2017-08-29, status=1, ipAttribution=)]
    2017-08-31 智智灵药

    #生存率#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1256594, encodeId=517c1256594a3, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466537, encodeId=7f4c146653e5f, content=<a href='/topic/show?id=621d6402097' target=_blank style='color:#2F92EE;'>#氧疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64020, encryptionId=621d6402097, topicName=氧疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8a786841989, createdName=rgjl, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238398, encodeId=3ffd23839835, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 29 19:44:06 CST 2017, time=2017-08-29, status=1, ipAttribution=)]
    2017-08-31 rgjl

    #氧疗#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1256594, encodeId=517c1256594a3, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466537, encodeId=7f4c146653e5f, content=<a href='/topic/show?id=621d6402097' target=_blank style='color:#2F92EE;'>#氧疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64020, encryptionId=621d6402097, topicName=氧疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8a786841989, createdName=rgjl, createdTime=Thu Aug 31 04:55:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238398, encodeId=3ffd23839835, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 29 19:44:06 CST 2017, time=2017-08-29, status=1, ipAttribution=)]
    2017-08-29 1e0ece0dm09(暂无匿称)

    谢谢分享

    0