Euro CMR:他汀类药物可改善心脏结构和功能

2017-08-06 佚名 Medicalnewsdaily

尽管使用他汀类药物治疗心脏病风险的患者在历史上颇有争议,但新的研究表明,他汀类药物可以通过改善心脏结构,从而促进心脏健康

尽管使用他汀类药物治疗心脏病风险的患者在历史上颇有争议,但新的研究表明,他汀类药物可以通过改善心脏结构,从而促进心脏健康。

他汀类药物是一种通常用于降低心脏病风险较高者的胆固醇水平的药物。

尽管他汀类药物的治疗用途受到争议,但在捷克共和国布拉格举行的EuroCMR提出的一项新研究表明,他汀类药物的益处超出了胆固醇降低的作用。

新研究的主要作者 - 伦敦皇后玛丽大学威廉·哈维研究所心脏病学家Nay Aung博士强调他汀类药物的健康益处。

它们可以通过防止血管扩张,增加斑块,减轻炎症,从而改善血管功能。

此外,以前的研究表明,它们可以减轻心肌的厚度,并推荐它们作为治疗左心室肥大的有益方式。

然而,这些研究主要在动物中进行,而人类的研究样本量相当小。因此,Aung博士和团队开始进行一项较大的研究,看他们是否可以确认这一项结论。

分析他汀类药物与心脏结构之间的联系

该研究检查了他汀类药物与心脏结构和功能之间的联系,观察了4,622例没有心血管疾病史的人。参与者参加了英国Biobank的一项大型研究。

该卫生资源包含患者使用他汀类药物的信息,研究人员使用问卷调查参与者了解他们使用他汀类药物的进一步信息。

研究人员使用心脏MRI来测量左心室和右心室的体积和质量。

Aung博士及其同事对数据进行了多元回归,调整了可能影响结果的因素,如身体质量指数(BMI),种族,种族和性别。

总体而言,近17%的参与者服用他汀类药物。这些患者往往年龄较大,BMI较高,血压升高,糖尿病较高。正如Aung博士解释的那样,这些协会预计,由于他汀类药物通常用于患者心脏病风险增加。高体重、高血压糖尿病都是已知的心脏疾病的危险因素。

他汀类药物可能会“逆转心脏的负面变化”

研究显示,用他汀类药物治疗的人整体结构和心脏功能全面。

具体来说,使用他汀类药物的患者发生增厚的心肌或左心室肥大的可能性较小,心脏室扩大的可能性较小。

“拥有厚厚的大心脏是未来心脏病发作,心力衰竭或中风的重要预测因子,并且服用他汀类药物似乎扭转了心脏的负面变化,从而降低了不良后果的风险。”翁博士

虽然这项研究是观察性的,但Aung博士就他汀类药物的心脏厚度和体积减少可能有一些可能的解释。他提到以前的研究显示,他汀类药物能够减少氧化应激并抑制促进细胞生长的因素的产生。

氧化应激是当自由基没有被抗氧化剂正确消灭时,身体发生的生理压力。氧化应激与老化有关。

一些研究还表明,他汀类药物由于其减少氧化应激而降低室性心律失常的风险。

“值得注意的是,在我们的研究中,与健康对照组相比,服用他汀类药物的人群患心脏病的风险高于那些不使用他汀类药物,但与健康对照组相比,他们仍然有积极的心脏重塑。”Aung博士补充说。

Aung博士还就最近辩论谁应该服用他汀类药物进行辩论:

“有明确规定谁应该接受他汀类药物。有争论是否应该降低了吧,问题是当你停止。我们发现,对于已经服用他汀类药物的患者,也有有益的影响超出降胆固醇,这是一件好事。但不是包治百病的药方我们需要识别那些最有可能受益即个性化医疗。"

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-12-06 guozhenyu
  2. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-11-01 jyzxjiangqin

    他汀类药物可改善心脏结构和功能.

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-10-09 jyzxjiangqin

    他汀类药物的作用.

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-09-14 Ashman

    增加斑块?防止扩张?

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1685420, encodeId=ddea16854201b, content=<a href='/topic/show?id=982b4908df' target=_blank style='color:#2F92EE;'>#CMR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4908, encryptionId=982b4908df, topicName=CMR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b85328187249, createdName=guozhenyu, createdTime=Wed Dec 06 07:40:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044465, encodeId=bd8a204446565, content=<a href='/topic/show?id=644725344b1' target=_blank style='color:#2F92EE;'>#他汀类药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25344, encryptionId=644725344b1, topicName=他汀类药)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Nov 27 23:40:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257687, encodeId=235925e68774, content=他汀类药物可改善心脏结构和功能., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 01 07:10:46 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251472, encodeId=9ee72514e2e2, content=他汀类药物的作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Oct 09 07:33:10 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244030, encodeId=b2872440304d, content=增加斑块?防止扩张?, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85ba1934117, createdName=Ashman, createdTime=Thu Sep 14 20:36:34 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616007, encodeId=2027161600e77, content=<a href='/topic/show?id=120f516469e' target=_blank style='color:#2F92EE;'>#心脏结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51646, encryptionId=120f516469e, topicName=心脏结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d41019719888, createdName=12498adam46暂无昵称, createdTime=Mon Aug 07 23:40:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230651, encodeId=f6042306516f, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Aug 06 08:52:24 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-08-06 明月清辉

    谢谢分享,学习了

    0

相关资讯

JAMA:连发两篇专家观点,聚焦降脂进展和争议!

2017年7月24日,JAMA在线发表了两篇Viewpoint,一篇探讨2017降脂治疗决策,另一篇则关注不同指南的推荐差异以及针对LDL-C的争议。作者分别由来自耶鲁大学医学院和斯坦福大学的两位专家。

Int J Antimicrob Ag:他汀或是对抗隐球菌感染的新武器

由隐球菌病感染导致的肺炎和脑膜炎,并具有高死亡率。新型隐球菌C. gattii的毒性更大,标准的抗真菌治疗反应差。目前隐球菌病的治疗选择很少,已有的抗真菌药物因存在弊端尔使用受限,包括氟康唑(FLC)耐药和两性霉素的副作用。2017年6月,发表在《Int J Antimicrob Agents》的一项研究显示,阿托伐他汀(ATO)+FLC治疗的感染小鼠存活率增加。

J Am Heart Assoc:我国台湾学者研究称,中风半年内停用他汀有危险

近期,发表在《美国心脏协会杂志》的一项中国台湾研究表明,首次缺血性中风发作后3~6个月内如果停用他汀,1年内中风复发的风险显着增加。

善用他汀,逆转斑块!——如何利用他汀逆转ASCVD患者斑块

动脉粥样硬化性心血管疾病(atherosclerotic cardiovascular disease,ASCVD )包括冠心病、动脉粥样硬化性卒中和外周血管疾病,病理基础是动脉粥样硬化(AS)。AS是脂代谢紊乱和炎症性血管疾病,随着疾病发展,血管堵塞程度加重,最终可能导致血管彻底阻塞。

BMC Cardiovasc Disord:新研究支持中国糖尿病患者使用他汀,他汀可使死亡和心血管病风险减半

香港大学学者近期报告,对于糖尿病患者的一级预防,支持低密度脂蛋白胆固醇(LDL-C)降得越低,获益越大的观点。 如果使LDL-C降至2.6 mmol/L以下,心血管病风险和全因死亡风险均降低50%以上。 研究者回顾性观察了10 104例糖尿病患者,并与对照组进行了匹配。 研究发现,与未应用他汀者相比,他汀应用者的LDL-C水平降低了1.21 mmol/L。 在中位随访50.5个月后,应用他

Int J Antimicrob Agents:多学科讨论:他汀或是对抗隐球菌感染的新武器

由隐球菌病感染导致的肺炎和脑膜炎,并具有高死亡率。新型隐球菌C. gattii的毒性更大,标准的抗真菌治疗反应差。目前隐球菌病的治疗选择很少,已有的抗真菌药物因存在弊端尔使用受限,包括氟康唑(FLC)耐药和两性霉素的副作用。2017年6月,发表在《Int J Antimicrob Agents》的一项研究显示,阿托伐他汀(ATO)+FLC治疗的感染小鼠存活率增加。