JAMA:使用固体燃料是造成中国农村地区心血管死亡高风险的重要因素

2018-04-08 zhangfan MedSci原创

研究发现,在中国农村地区使用固体燃料与心血管死亡以及全因死亡风险增加相关,普及清洁燃料并改善通风可显著降低这一风险

固体燃料在室内燃烧时会产生大量的细颗粒物污染物,是潜在的呼吸系统和心血管风险因素。近日研究人员就烹调和取暖过程中固体燃料使用与心血管和全因死亡率之间的关系进行了考察。

研究在中国5个农村地区开展。参与者放弃使用传统固体燃料(煤、木头或木炭)转换使用清洁燃料(煤气、电或集中供热)或安装通风炉灶,总计271217名无基线心血管疾病史患者参与,在2.7年后进行心血管疾病复查。研究的主要终点是心血管以及全因死亡率。

参与者平均年龄51.0岁,女性占59%。66%的参与者经常做饭,60%的参与者冬天取暖。在做饭以及取暖的参与者中,分别有84%和90%的人群使用固体燃料。在7.2年的随访过程中总计死亡15468人,其中心血管死亡5519人。研究发现使用固体燃料做饭导致心血管死亡风险(每100000患者年绝对风险差异135,HR=1.20)以及全因死亡风险(每100000患者年绝对风险差异338,HR=1.11)显著增加。固体燃料取暖导致心血管死亡风险(每100000患者年绝对风险差异175,HR=1.29)以及全因死亡风险(每100000患者年绝对风险差异392,HR=1.14)显著增加。相比于继续使用固体燃料人群,转换清洁能源做饭可显著降低心血管死亡(HR=0.83)以及全因死亡(HR=0.87)风险,而清洁能源取暖降低参与者心血管死亡(HR=0.57)以及全因(HR=0.67)死亡风险效果更为显著。对于使用固体燃料人群,安装通风炉灶也可以降低心血管死亡(HR=0.89)以及全因(HR=0.87)死亡风险。

研究发现,在中国农村地区使用固体燃料与心血管死亡以及全因死亡风险增加相关,普及清洁燃料并改善通风可显著降低这一风险。

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    2018-04-10 daviiliu
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    2018-04-08 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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