J Gastroen Hepatol:结肠内镜下黏膜切除术后出血因素研究

2017-10-22 zhangfan MedSci原创

血管切割、严重凝血性损伤以及息肉大小是导致延迟息肉出血的危险因素。研究认为术后溃疡检查和预防性止血,可提高结肠内镜下黏膜切除术的临床疗效

出血是内镜下黏膜切除术后(EMR)最常见的不良事件。近日研究人员根据EMR后溃疡状态评估了结肠EMR的临床效果以及术后延迟息肉出血的危险因素(DPPB)。

研究人员收集结肠息肉直径5mm患者的医疗记录、电子病历与内窥镜图像进行回顾性分析。术后溃疡暴露血管可分为进行切割或未切割血管。EMR伤后的凝血损伤分为1-3级。

505名患者以及728个息肉标本参与研究。溃疡状态评估发现了416例血管暴露,包括11例切割血管以及405例未切割血管。依据凝血损伤,1-3级损伤患者分别有113例 (15.5%), 443例 (60.9%)和172 例(23.6%)。20名患者 (2.7%)发生延迟息肉出血,多因素分析显示,> 10 mm息肉(OR,3.354;95% CI,1.229–9.154)、切开的血管(OR,18.913;95% CI,3.106–115.187)以及 3级凝血损伤(OR,16.796;95% CI, 2.825–154.556) 与DPPB相关。

血管切割、严重凝血性损伤以及息肉大小是导致延迟息肉出血的危险因素。研究认为术后溃疡检查和预防性止血,可提高结肠内镜下黏膜切除术的临床疗效。

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    2018-05-11 许安
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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-24 海之蓝

    学习

    0

  5. 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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-23 docwu2019
  6. 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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-23 gwc384
  7. 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encodeId=44562554216a, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Oct 23 21:16:57 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=255057, encodeId=962325505e47, content=谢谢分享. , beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Oct 22 09:20:06 CST 2017, time=2017-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=255038, encodeId=cfea2550389f, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-23 snowpeakxu
  8. [GetPortalCommentsPageByObjectIdResponse(id=1876957, encodeId=c12118e6957c4, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon May 14 15:03:00 CST 2018, time=2018-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711222, encodeId=1fef1e1122229, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, 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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-23 thlabcde

    好资料学习了!

    0

  9. 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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-22 doctorJiangchao

    谢谢分享.

    0

  10. 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content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun Oct 22 08:07:06 CST 2017, time=2017-10-22, status=1, ipAttribution=)]
    2017-10-22 榄枷檬

    谢谢分享

    0