Allergy:中国艾属花粉过敏研究

2018-09-07 AlexYang MedSci原创

在中国北部,艾属花粉过敏是哮喘重要的过敏原。lgE对艾属花粉过敏原组分的响应与临床表型之间的可能相关性还没有评估。最近,有研究人员建立了4种艾属花粉过敏原的敏感模式,并在中国3个地区探究了与人口特性和临床表型之间可能的相关性。研究包括了240名对艾属花粉过敏的患者,其中178名来自陕西省,30名来自山东省,32名赖在云南省。研究人员诊断了过敏性哮喘、鼻炎、结膜炎和湿疹症状。所有患者的血清通过Imm

在中国北部,艾属花粉过敏是哮喘重要的过敏原。lgE对艾属花粉过敏原组分的响应与临床表型之间的可能相关性还没有评估。最近,有研究人员建立了4种艾属花粉过敏原的敏感模式,并在中国3个地区探究了与人口特性和临床表型之间可能的相关性。

研究包括了240名对艾属花粉过敏的患者,其中178名来自陕西省,30名来自山东省,32名赖在云南省。研究人员诊断了过敏性哮喘、鼻炎、结膜炎和湿疹症状。所有患者的血清通过ImmunoCAP进行测试,具体使用了艾蒿花粉提取物和自然组分nArt v 1、 nArt ar 2、nArt v 3和nArt an 7。研究发现,中国西南地区的艾属花粉过敏患者对4种组分lgE水平和敏感频率要比中国北部患者显著更低。Art v 1和Art an 7是最常见的过敏原(分别为(84%和87%),Art v 3和Art ar 2分别为66%和48%。另外,来自中国北部的患者比中国西南部的患者更可能患有过敏性哮喘(50%),并且对不少于2种的过敏原过敏增加了过敏性哮喘的风险,其中对3种主要过敏原Art v 1、Art v 3和Art an 7的共同过敏比较显著。

最后,研究人员指出,中国艾属花粉过敏组分确定诊断能够帮助评估艾蒿相关过敏性哮喘潜在的风险。

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    2018-09-09 膀胱癌
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    2018-09-08 lietome24

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

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