Am J Med:成人拉克罗斯脑炎回顾性研究

2016-08-06 Mechront 译 MedSci原创

背景和目的:目前对于儿童拉克罗斯病毒性脑炎已经有了很好的认识,但是对于成年患者,当前相关文献只有2例案例。儿童感染该疾病常可危及生命,通常表现为发热性脑膜脑炎、癫痫和精神状态的变化;成人感染该疾病是否有类似表现?方法:对2001-2012年之间,可疑成年人(≥18岁)拉克罗斯脑炎患者的住院资料进行回顾性分析。结果:确诊了10例成年人拉克罗斯病毒性脑炎,年龄从20岁到80岁不等。主要的表现有:发热、

背景和目的:目前对于儿童拉克罗斯病毒性脑炎已经有了很好的认识,但是对于成年患者,当前相关文献只有2例案例。儿童感染该疾病常可危及生命,通常表现为发热性脑膜脑炎、癫痫和精神状态的变化;成人感染该疾病是否有类似表现?

方法:对2001-2012年之间,可疑成年人(≥18岁)拉克罗斯脑炎患者的住院资料进行回顾性分析。

结果:确诊了10例成年人拉克罗斯病毒性脑炎,年龄从20岁到80岁不等。主要的表现有:发热、头痛、低钠血症。5名患者出现了癫痫,2名患者出现了精神状态变化。

平均住院天数为8.4天(±8.4);3名患者转入ICU治疗,其中2名患者进行了气管插管;4名患者出院到康复机构。

结论:成人感染拉克罗斯病毒会产生显著性脑炎的临床表现,应对其保持高度怀疑,尤其是在流行地区。虽然回顾的确诊病例中无死亡发生,但是成人拉克罗斯脑炎仍是与心理状态变化相关联的病态疾病,其住院时间长、出院后所需康复时间长。

原始出处:

Teleron AL.et al.La Crosse Encephalitis: An Adult Case Series.Am J Med. 2016 Aug;129(8):881-4. doi: 10.1016/j.amjmed.2016.03.021

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    2016-10-09 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

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    2016-10-09 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

  3. 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    2016-10-03 1e0ece0dm09(暂无匿称)

    谢谢谢谢

    0

  4. 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objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40556, encryptionId=e76840556f9, topicName=回顾性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=037917278808, createdName=jiyangfei, createdTime=Mon Aug 08 02:51:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607017, encodeId=09e6160e017c6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 08 02:51:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96568, encodeId=c3789656811, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Aug 06 23:24:00 CST 2016, time=2016-08-06, status=1, ipAttribution=)]
    2016-09-03 李东泽

    很好,不错,以后会多学习

    0

  5. 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encodeId=c3789656811, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Aug 06 23:24:00 CST 2016, time=2016-08-06, status=1, ipAttribution=)]
    2016-08-12 吴教授

    学习了,罕见疾病。

    0

  6. 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encodeId=c3789656811, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Aug 06 23:24:00 CST 2016, time=2016-08-06, status=1, ipAttribution=)]
    2016-08-09 忠诚向上

    好好学习

    0

  7. 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  8. 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  9. 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  10. 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    2016-08-06 忠诚向上

    好好学习

    0