BJC:身高越高,非黑素瘤皮肤癌风险越高!

2016-11-21 MedSci MedSci原创

成人身高已与一些特定部位的癌症风险有关,包括黑色素瘤。但是身高与非黑素瘤皮肤癌(NMSC)之间的联系研究较少。 我们前瞻性地研究了成人身高与鳞状细胞癌(SCC)和基底细胞癌(BCC)风险之间的联系,研究对象为护士健康研究(NHS, n=117 863)和卫生专业人员随访研究(HPFS, n=51 111)中的参与者。 我们还研究了身高相关遗传标记与BCC和SCC风险间的联系,其中389

成人身高已与一些特定部位的癌症风险有关,包括黑色素瘤。

但是身高与非黑素瘤皮肤癌(NMSC)之间的联系研究较少。

我们前瞻性地研究了成人身高与鳞状细胞癌(SCC)和基底细胞癌(BCC)风险之间的联系,研究对象为护士健康研究(NHS, n=117 863)和卫生专业人员随访研究(HPFS, n=51 111)中的参与者。

我们还研究了身高相关遗传标记与BCC和SCC风险间的联系,其中3898例BCC患者,8530例BCC对照者,527例SCC患者,8962例SCC8962 SCC。

控制潜在的混杂因素后,身高每增加10cm,SCC和BCC的HR值分别为1.09 (95% CI: 1.02, 1.15)和1.10 (95% CI: 1.07, 1.13)。687个身高相关遗传标记与BCC和SCC风险无关。

来自两个大型队列研究的数据表明,身高越高,NMSC风险越高。

原始出处:


Xin Li1, Liming Liang1,et al.Height, height-related SNPs, and risk of non-melanoma skin cancer.British Journal of Cancer advance online publication 15 November 2016

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    2017-05-07 sjq027
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    2017-01-22 wmu姿

    还有这种关系,开眼界了

    0

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    2016-12-05 laoli

    谢谢分享,学习了!

    0

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    2016-11-21 䖝二

    这也可以!

    0

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