Diabetes Care:耐力锻炼可更持续降低血糖

2012-12-05 高晓方译 Diabetes Care

     加拿大学者的一项研究表明,与有氧锻炼相比,耐力锻炼期间血糖初始降低程度较小,但运动后血糖降低持续时间较长。论文于2012年11月19日在线发表于《糖尿病护理》(Diabetes Care)杂志。   此项研究共纳入12例平素进行体能活动的1型糖尿病患者。受试者进行45分钟耐力锻炼、45分钟有氧锻炼或在间隔期不进行锻炼。在锻炼期间和之后60分钟测定血糖。利用持续血糖监测在锻炼

  耐力锻炼

  加拿大学者的一项研究表明,与有氧锻炼相比,耐力锻炼期间血糖初始降低程度较小,但运动后血糖降低持续时间较长。论文于2012年11月19日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  此项研究共纳入12例平素进行体能活动的1型糖尿病患者。受试者进行45分钟耐力锻炼、45分钟有氧锻炼或在间隔期不进行锻炼。在锻炼期间和之后60分钟测定血糖。利用持续血糖监测在锻炼前24小时、期间和后24小时测定组织血糖。

  结果显示,锻炼期间和之后血糖变化存在时间治疗交互作用(P<0.001)。耐力锻炼期间血糖由(8.46±2.7)mmol/L降低至(6.86±2.3)mmol/L(P=0.008),有氧锻炼期间由(9.26±3.4)mmol/L降低至(5.86±2.0)mmol/L(P=0.001)。未锻炼对照期间血糖无显著变化。耐力锻炼后血糖水平无显著变化,有氧锻炼后则升高(2.26±0.6)mmol/L(P=0.023)。耐力锻炼后4.5~6小时平均组织血糖显著低于有氧锻炼后血糖。

 


OBJECTIVE 
In type 1 diabetes, small studies have found that resistance exercise (weight lifting) reduces HbA1c. In the current study, we examined the acute impacts of resistance exercise on glycemia during exercise and in the subsequent 24 h compared with aerobic exercise and no exercise.
RESEARCH DESIGN AND METHODS 
Twelve physically active individuals with type 1 diabetes (HbA1c 7.1 ± 1.0%) performed 45 min of resistance exercise (three sets of seven exercises at eight repetitions maximum), 45 min of aerobic exercise (running at 60% of VO2max), or no exercise on separate days. Plasma glucose was measured during and for 60 min after exercise. Interstitial glucose was measured by continuous glucose monitoring 24 h before, during, and 24 h after exercise.
RESULTS 
Treatment-by-time interactions (P < 0.001) were found for changes in plasma glucose during and after exercise. Plasma glucose decreased from 8.4 ± 2.7 to 6.8 ± 2.3 mmol/L (P = 0.008) during resistance exercise and from 9.2 ± 3.4 to 5.8 ± 2.0 mmol/L (P = 0.001) during aerobic exercise. No significant changes were seen during the no-exercise control session. During recovery, glucose levels did not change significantly after resistance exercise but increased by 2.2 ± 0.6 mmol/L (P = 0.023) after aerobic exercise. Mean interstitial glucose from 4.5 to 6.0 h postexercise was significantly lower after resistance exercise versus aerobic exercise.
CONCLUSIONS 
Resistance exercise causes less initial decline in blood glucose during the activity but is associated with more prolonged reductions in postexercise glycemia than aerobic exercise. This might account for HbA1c reductions found in studies of resistance exercise but not aerobic exercise in type 1 diabetes.    

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