空气污染伤大脑:降低脑容量 增隐匿性脑梗死风险

2015-04-29 小田 译 cmt

既往研究表明,长期暴露于污染的空气中与脑血管疾病和认知损害有关,但是否与大脑结构变化有关尚不清楚。近期,美国一项研究表明,暴露于PM2.5水平升高的环境与人体总脑容量较小有关,后者是年龄相关脑萎缩的标志,同时还能导致隐匿性脑梗死发生率较高。研究结果提示,空气污染可能对人体大脑结构老化有潜在有害的影响,甚至是对无痴呆和卒中的人群也存在上述影响。相关论文4月23日在线发表于《卒中》(Stroke)杂志

既往研究表明,长期暴露于污染的空气中与脑血管疾病和认知损害有关,但是否与大脑结构变化有关尚不清楚。近期,美国一项研究表明,暴露于PM2.5水平升高的环境与人体总脑容量较小有关,后者是年龄相关脑萎缩的标志,同时还能导致隐匿性脑梗死发生率较高。研究结果提示,空气污染可能对人体大脑结构老化有潜在有害的影响,甚至是对无痴呆和卒中的人群也存在上述影响。相关论文4月23日在线发表于《卒中》(Stroke)杂志。



研究纳入了弗明翰子代研究年龄至少60岁且无痴呆和卒中的受试者。评估暴露于空气细颗粒物(PM2.5)和居住在公路要道与受试者总脑容量、海马体积、脑白质高信号体积和隐匿性脑梗死的关系。校正年龄、临床变量、社会经济学等因素。结果显示,PM2.5每增加2-μg/m3与总脑容量下降0.32%和隐匿性脑梗死发生率增加46%有关。

原始出处:

Elissa H. Wilker,  Sarah R. Preis,  Alexa S. Beiser,  Philip A. Wolf,et al.Long-Term Exposure to Fine Particulate Matter, Residential Proximity to Major Roads and Measures of Brain Structure.Stroke.April 23, 2015,doi: 10.1161/STROKEAHA.114.008348

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    2015-05-01 karmond
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    2015-05-01 aids218
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    2015-04-30 medcardio

    真有证据了

    0

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