Diabetes Care:妊娠前超重和肥胖可导致大于胎龄儿增多

2012-08-21 高晓方 医学论坛网

  美国学者的一项研究表明,即便在无妊娠糖尿病(GDM)的情况下,妊娠前超重和肥胖仍可导致大于胎龄儿(LGA)出现率升高。论文于2012年8月13日在线发表于《糖尿病护理》(Diabetes Care)杂志。   此项回顾性研究共纳入9835例在妊娠20周以后分娩的女性受试者。受试者接受产前口服葡萄糖耐量检测,并且在妊娠期间未接受膳食、运动或降糖药治疗。基于IADPSG标准诊断GDM,

  美国学者的一项研究表明,即便在无妊娠糖尿病(GDM)的情况下,妊娠前超重和肥胖仍可导致大于胎龄儿(LGA)出现率升高。论文于2012年8月13日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  此项回顾性研究共纳入9835例在妊娠20周以后分娩的女性受试者。受试者接受产前口服葡萄糖耐量检测,并且在妊娠期间未接受膳食、运动或降糖药治疗。基于IADPSG标准诊断GDM,并利用BMI进行受试者分类。

  结果显示,超重和罹患GMD的受试者分别占59.5%和19.2%。76.3%的GDM患者伴有肥胖或超重。在无GDM的超重和肥胖女性中LGA的出现率显著高于体重正常者。在无GDM的女性中,21.6%的LGA由母体超重和肥胖所致;肥胖或超重联合GDM则导致了23.3%的LGA。妊娠体重增长幅度升高与LGA出现率较高相关。

  链接:Mary Helen Black, David A. Sacks, Anny H. Xiangand Jean M. Lawrence,The Relative Contribution of Prepregnancy Overweight and Obesity, Gestational Weight Gain, and IADPSG-Defined Gestational Diabetes Mellitus to Fetal Overgrowth.Diabetes Care



    

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