糖尿病高血压是老年动脉僵硬度增高的影响因素

2012-04-25 小哲 摘编 医学论坛网

  近日,北京大学第三医院老年内科刘喆、王海宁、王峥嵘等人共同发表论文,旨在评价老年高血压和(或)糖尿病患者动脉僵硬度及其影响因素。研究指出,糖尿病、高血压是老年人动脉僵硬度增高的影响因素,而高血糖对老年人动脉僵硬度的影响可能起了更重要的作用。血糖、平均动脉压、脉压、超每C反应蛋白、低密度脂蛋白胆固醇均是影响动脉僵硬度的独立危险因素。该文发表在2012年第31卷第1期《中华老年医学杂志》上。  

  近日,北京大学第三医院老年内科刘喆、王海宁、王峥嵘等人共同发表论文,旨在评价老年高血压和(或)糖尿病患者动脉僵硬度及其影响因素。研究指出,糖尿病、高血压是老年人动脉僵硬度增高的影响因素,而高血糖对老年人动脉僵硬度的影响可能起了更重要的作用。血糖、平均动脉压、脉压、超每C反应蛋白、低密度脂蛋白胆固醇均是影响动脉僵硬度的独立危险因素。该文发表在2012年第31卷第1期《中华老年医学杂志》上。

  320例老年患者分为4组:对照组、糖尿病组、高血压组、高血压并存糖尿病组(联合患病组)。收集年龄、体质指数、性别、吸烟、血压、脉压及平均动脉压,测定血清空腹血糖、血脂、糖化血红蛋白、超敏C反应蛋白等;并应用COLIN-VP1000动脉硬化测定仪测量入选者踝臂脉搏波传导速度(baPWV)以评价对动脉硬化的影响。

  结果联合患病组、高血压组及糖尿病组的baPWV水平与对照组比较,差异均有统计学意义,联合患病组与糖尿病组的baPWV值比较,差异无统计学意义,高血压组与糖尿病组及联合患病组的baPWV值比较,差异有统计学意义。联合患病组脉压、超敏C反应蛋白最高,与对照组比较,差异有统计学意义。多元线性回归分析结果显示,血清空腹血糖、平均动脉压、脉压、超敏C反应蛋白、低密度脂蛋白胆固醇与baPWV水平呈正相关。

  相关链接:老年高血压和糖尿病患者动脉僵硬度的影响因素分析



    

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    2012-04-27 liuxiaona
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    2012-04-27 liuxiaona

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