JAMA Neurol:慢性单侧上运动神经元病变步态障碍的临床干预

2018-03-02 zhangfan MedSci原创

目前认为步态障碍的认识和治疗尚需要一个过程,基于证据而非经验的医药以及医技干预是克服这一医学难题的希望

步态障碍在慢性幕上运动神经元病变中很常见,是致残的原因之一。目前而言,步态障碍的临床治疗是一项极具挑战性的任务,治疗效果存在极大的不可确定性。目前的干预手段主要包括:辅助设备、肌肉伸展、药物治疗和外科干预,但大多数治疗方法的证据性低,而且缺乏明确的治疗指南。

慢性幕上运动神经元病变成人的步态异常大致存在3组原发性缺陷:(1)肌肉力量、长度、踝关节及跖关节周围活动的不平衡导致马蹄内翻足或马蹄内斑疹;(2)小腿肌肉无力;(3)腿近端肌肉过度活动。

目前认为步态障碍的认识和治疗尚需要一个过程,基于证据而非经验的医药以及医技干预是克服这一医学难题的希望。

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    2018-10-14 xxxx1061
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    2018-09-28 yinhl1978
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