Int J Cardiol:16万国人血脂异常新数据!五分之一HDL-C低,13%甘油三酯高

2018-05-09 卢芳 中国循环杂志

近期,中国疾病预防控制中心(CDC)Zhang M等就2013~2014年全国16万余成年居民的血脂异常情况进行了调查分析,结果不容乐观。


近期,中国疾病预防控制中心(CDC)Zhang M等就2013~2014年全国16万余成年居民的血脂异常情况进行了调查分析,结果不容乐观。
 
研究显示,整体人群中,总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)的人群加权平均值分别为4.70mmol/L、1.35 mmol/L和2.88 mmol/L;甘油三酯(TG)中位数为1.49mmol / L。
 
高胆固醇血症(TC ≥ 6.22 mmol/L)的患病率为6.9%,高LDL-C血症(LDL-C ≥ 4.14 mmol/L)患病率为8.1%,低HDL-C血症(HDL-C<1.04 mmol/L)患病率为20.4%,高甘油三酯血症患病率(TG ≥ 2.26 mmol/L)为13.8%。
 
就动脉粥样硬化性心血管疾病(ASCVD)高危或极高危者而言,研究估计约占人群10%。

但在高危人群中有74.5%的人LDL-C水平未达标(<2.6 mmol / L),其中5.5%接受了降脂治疗;极高危人群中93.2%的人LDL-C未达标(<1.8mmol / L),其中14.5%接受了降脂治疗。
 
整体来看,男性较女性有更高的TC和LDL-C平均值、中位TG值以及更低的HDL-C平均值。人群TC和LDL-C水平随年龄、家庭收入以及体重指数的增加而增加,而随教育程度增加而降低。
 
多因素回归分析显示,男性较女性低HDL-C血症和高甘油三酯血症的风险更高,而高胆固醇血症风险更低。
 
此外,超重或肥胖、中心性肥胖以及吃红肉过多(≥100g/d)会显著增加男性和女性高胆固醇血症和高LDL-C血症。城市居住、体重指数≥24 kg/m2、吸烟或饮酒均与高甘油三酯血症相关。
 
研究者介绍说,该研究高胆固醇血症、高LDL-C血症、低HDL-C血症和高甘油三酯血症的患病率均较2002年中国营养与健康调查结果显著较高(2.9%、2.5%、7.4%和11.9%);但与最近对2007~2010年和2007年进行的两项全国性研究数据相比,则高胆固醇血症、高LDL-C血症、低HDL-C血症患病率略降低。
 
这项研究中纳入的163641位受试者来源于2013-2014中国慢性病和危险因素监测(CCDRFS)调查,其中男性占42.6%;平均年龄在男性为51.6岁,在女性为51.4岁。
 
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    2018-05-14 cscdliu

    学习了.谢谢

    0

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    2018-05-11 ZGMFX24A
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    2018-05-10 yfjms

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