“A-PePSI LIGhT”评估分数可预测压疮愈合受损的危险因素

2022-02-17 MedSci原创 MedSci原创

据报道,压疮手术后并发症发生率高达46%。尽管采用了无张力皮瓣覆盖,但压疮患者术后伤口愈合往往无效,需要手术修复和延长住院时间。

据报道,压疮手术后并发症发生率高达46%。尽管采用了无张力皮瓣覆盖,但压疮患者术后伤口愈合往往无效,需要手术修复和延长住院时间。与压疮复发不同,这种受损的愈合反映了正常伤口愈合级联的生理阶段的失败进展。

该研究的主要目的是阐明潜在的可修改的内在变量,来预测损伤愈合的前驱部位,并为确定压疮重建后复杂的术后早期恢复风险病例提供一种工具。

图1文章来源

因此,研究团队对2014年至2019年间接受皮瓣重建的晚期(3期或以上)骶骨和坐骨压疮患者进行回顾性分析,并采用多变量逻辑回归模型用于确定关键患者和预测愈合受损的手术因素。此外,根据确定的风险因素,建立了预测压疮受损愈合的评估分数(A-PePSI)。

图2 对受调查队列中的每个个体计算该指数。受损愈合和充分愈合的分数和绝对分布以相应的A-PePSI值显示。当该指数大于或等于3时,大多数患者(73%)的愈合受损。Mann-Whitney U检验得出各类别之间的统计显著差异(*p<0.001)。IH,愈合受损;非常好的治疗。

结果显示,在121名患者的队列中,36%的患者表现出愈合受损。其中,34名患者出现裂开,需要手术翻修。统计上显著的风险因素包括晚期复发(OR,3.8)、无变化(OR,12.4)、较大创面(>5cm直径;OR,7.3)和血小板抑制(阿司匹林单一疗法;OR,5.7)被结合起来,形成一个预后评分系统(a-PepsiLight)。

这项研究有助于对晚期压疮患者的风险因素进行新的了解,从而能够以可靠的诊断准确性预测术后早期并发症。A-PePSI轻度风险评估可能是克服目前与压疮患者手术治疗相关的一些缺陷的更全面方法的基石之一。尽管作者承认临床决策本身就更复杂,但基于阐明的患者内在特征的术前风险分层可能有助于预判手术效果,允许循证患者咨询,并支持实施个体化治疗方案,以更好地提高整体重建成功率。

原始文章:

Anker Alexandra M,Ruewe Marc,Prantl Lukas et al. Prognostic Evaluation of Pressure Sore Surgery Index: Risk Assessment and Outcomes of a Retrospective Cohort Study.[J] .Plast Reconstr Surg, 2021, undefined: undefined.

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    2023-01-21 lq1767
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    2022-07-09 feather89
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    2022-02-18 ms3000000089219083

    学习

    0

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    2022-02-17 医鸣惊人

    认真学习了

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毕竟思密达在压疮等方面的应用,在教科书、压疮防治指南、还有药品说明书中都未提及,还是要慎用,基层医院的病人,压疮护理耗材费用难以承受、经济条件有限者,可以一试。

JTV:足跟专用医疗装置预防足跟压疮的有效性比较

低质量证据表明,足跟减压装置可降低HPUs发生率。没有足够的证据表明敷料可以降低HPUs的发病率。

2023 WHS指南:压疮(更新版)

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2016 WOCN指南:压疮的预防和管理

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2015 ACP临床实践指南:压疮的治疗

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2015 ACP临床实践指南: 压疮的治疗

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