Cell Mol Gastroenterol Hepatol:不饱和脂肪与脂肪肝疾病有关

2017-06-15 枫丹白露 来宝网

随着肥胖症的流行继续,新的数据揭示了哪些营养物质和营养物质的数量会促进健康或疾病。在美国消化科学协会杂志“细胞与分子胃肠病学与肝病学”杂志上,科学家们报告了大量营养素在代谢不健康肥胖症发病中的作用,患者以肥胖为根本原因,特别是非酒精性脂肪性肝病(NAFLD)。

随着肥胖症的流行继续,新的数据揭示了哪些营养物质和营养物质的数量会促进健康或疾病。在美国消化科学协会杂志“细胞与分子胃肠病学与肝病学”杂志上,科学家们报告了大量营养素在代谢不健康肥胖症发病中的作用,患者以肥胖为根本原因,特别是非酒精性脂肪性肝病(NAFLD)。

加利福尼亚大学旧金山分校(UCSF)的研究人员研究了两组摄入饱和脂肪或不饱和脂肪的饮食。令人惊讶的是,他们发现摄入淀粉和单不饱和脂肪酸油酸酯会导致脂肪肝病,类似高脂肪“西方饮食”的作用。

UCSF医学系和肝脏中心主任Caroline C. Duwaerts博士说:“虽然声称具有许多健康益处,包括有利的脂质分布,但过多的不饱和脂肪可能对新陈代谢产生重大不利影响。 “我们的研究增加了新的信息,以了解代谢不健康的肥胖症,并应该带来额外的研究重点,即饱和脂肪和不饱和脂肪及大量营养素浓度。

宾夕法尼亚大学的Rotonya Carr医生说:“这项研究清楚地表明,营养成分(不仅仅是总体的)在NAFLD的发病机理中起重要作用,并且支持其他组织的研究结果,其类似地证明高碳水化合物/高脂肪饮食的组合促进肝损伤。

单不饱和脂肪是一种不饱和脂肪,被认为有助于降低胆固醇水平,以代替饱和脂肪在人的饮食中。单不饱和脂肪包括油,如橄榄,花生和油菜,以及鳄梨和一些坚果和种子。认为在肉类,奶酪和黄油等基于动物的食物中发现的饱和脂肪被认为会引起不良胆固醇并导致心脏病风险增加。

原始出处:

Caroline C. Duwaerts, Amin M. Amin, et al. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cellular and Molecular Gastroenterology and Hepatology Volume 4, Issue 2, September 2017, Pages 223–236

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topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Sun Dec 03 11:19:00 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071801, encodeId=6d3020e180141, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Mon Apr 16 22:19:00 CST 2018, time=2018-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213079, encodeId=11082130e9fe, content=文章很好,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Jun 20 10:07:31 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426754, encodeId=1a431426e5450, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Sat Jun 17 13:19:00 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579974, encodeId=32a115e99746e, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Sat Jun 17 13:19:00 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211758, encodeId=b246211e5842, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jun 17 06:29:15 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-12-03 维他命
  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2018-04-16 许安
  6. 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href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Sat Jun 17 13:19:00 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211758, encodeId=b246211e5842, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jun 17 06:29:15 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-20 1e10c84am36(暂无匿称)

    文章很好,拜读了

    0

  7. 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href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Sat Jun 17 13:19:00 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211758, encodeId=b246211e5842, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jun 17 06:29:15 CST 2017, time=2017-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-17 gwc384
  8. 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  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-17 龙胆草

    学习谢谢分享

    0

  10. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211257, encodeId=d1c621125e7d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jun 15 22:34:19 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-15 天地飞扬

    学习了,谢谢分享!

    0

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近日发表于PLOS Medicine的一项新的研究表明,多吃不饱和脂肪而非碳水化合物可降低患2型糖尿病的风险。新的荟萃分析显示,将碳水化合物和饱和脂肪更换为健康的脂肪,如多不饱和脂肪,可降低血糖水平,并改善胰岛素控制。世界范围内,胰岛素抵抗和2型糖尿病的发病率正急剧上升。据CDC统计,美国约有2910万人患有糖尿病,占总人口的9.3%左右。为此,CDC呼吁人们健康饮食,定期锻炼,并使用降糖药物治疗

JAMA Intern Med:这些膳食脂肪可以降低死亡率

背景:以前的研究已经显示出特定的饮食脂肪和心血管疾病之间的不同的关联。然而,具体的饮食脂肪和死亡率的证据仍然是有限的和不一致的。目的:在2项正在进行里的大型队列研究中,探究特定的饮食脂肪与全因和特定原因死亡率之间的关系。方法:该队列研究纳入了来自护士健康研究的83349名妇女和卫生专业人员随访研究的42884名男性;基线均没有心血管疾病、癌症和1/2型糖尿病。在基线评估膳食脂肪的摄入量,每2至4年