Genome Biology:食物会影响DNA序列

2016-11-20 叶予 生物通

牛津大学的研究人员在两种寄生虫中检测到了食物组分造成的DNA序列差异。他们在Genome Biology杂志上发表文章指出,食物能够影响生物的基因序列。“生物从食物中获取原料构建自己的DNA。我们认为,食物组分可能应该能够改变生物的DNA。我们也许可以预测素食者熊猫与肉食者北极熊之间的基因差异,” 牛津大学的Dr Steven Kelly说。为了测试这个理论,研究人员选择两种寄生虫作为模式生物,一

牛津大学的研究人员在两种寄生虫中检测到了食物组分造成的DNA序列差异。他们在Genome Biology杂志上发表文章指出,食物能够影响生物的基因序列。

“生物从食物中获取原料构建自己的DNA。我们认为,食物组分可能应该能够改变生物的DNA。我们也许可以预测素食者熊猫与肉食者北极熊之间的基因差异,” 牛津大学的Dr Steven Kelly说。

为了测试这个理论,研究人员选择两种寄生虫作为模式生物,一种真核生物寄生虫(Kinetoplastida)和一种细菌寄生虫(Mollicutes)。这些寄生虫有共同的祖先,但它们感染不同的宿主,食物也大不相同。“我们发现,寄生虫食物中不同水平的氮造成了它们的DNA改变。具体来说,与摄取高氮高蛋白食物的寄生虫相比,摄取低氮高糖食物的寄生虫DNA使用更少的氮,”Kelly表示。

这些结果揭示了过去人们不曾发现的细胞代谢与进化之间的关系。研究表明,生物对不同食物的适应会影响它们的DNA。此外,通过分析近亲物种的DNA序列可以预测它们的食物。


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    2017-01-25 sunylz
  3. [GetPortalCommentsPageByObjectIdResponse(id=1767053, encodeId=d1681e67053ae, content=<a href='/topic/show?id=64f5343e2f' target=_blank style='color:#2F92EE;'>#Biol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3437, encryptionId=64f5343e2f, topicName=Biol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Tue Dec 27 23:20:00 CST 2016, time=2016-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917345, encodeId=52bf191e345d8, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Jan 25 06:20:00 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416742, encodeId=7aaf1416e420b, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Tue Nov 22 02:20:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157204, encodeId=de1f15e20410, content=怎么不是相同的寄生虫在不同的环境与食物摄入的研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Nov 21 08:22:25 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157054, encodeId=7ec515e05404, content=话说这就是古语所云,病从口入。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160807/IMG57A72B38A8C787546.jpg, createdBy=52b31714117, createdName=Anima, createdTime=Sun Nov 20 12:51:00 CST 2016, time=2016-11-20, status=1, ipAttribution=)]
    2016-11-22 yhy100201
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    2016-11-21 cqykthl

    怎么不是相同的寄生虫在不同的环境与食物摄入的研究

    0

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    2016-11-20 Anima

    话说这就是古语所云,病从口入。

    0

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