Oncotarget:6类植物提取物能够延缓衰老

2016-03-22 生物谷 生物谷

不老泉”也许只是一个传说,但这从未阻止科学家们寻找科学地获得“长生”的脚步。近年来,研究者们对rapamycin、metformin等药物的兴趣浓厚,主要在于它们能够有效地延长寿命并且有治疗疾病的能力。然而,最近一项研究表明这些药物的抗衰老能力已经不再独树一帜了:一些植物提取物含有目前已知最强的抗衰老特性。来自加拿大Concordia大学的研究者们进行了10000多次筛选试验,看那些植物提取物能够

不老泉”也许只是一个传说,但这从未阻止科学家们寻找科学地获得“长生”的脚步。近年来,研究者们对rapamycin、metformin等药物的兴趣浓厚,主要在于它们能够有效地延长寿命并且有治疗疾病的能力。

然而,最近一项研究表明这些药物的抗衰老能力已经不再独树一帜了:一些植物提取物含有目前已知最强的抗衰老特性。

来自加拿大Concordia大学的研究者们进行了10000多次筛选试验,看那些植物提取物能够有效延长酵母的成活周期。

你可能想象不到,酵母是研究生命长度领域最常见的模式生物,这主要是因为酵母与人类细胞水平的寿命相仿。

“总之,我们发现有6种分子能够有效延缓酵母的生活周期”,来自Concordia大学的研究者Vladimir Titorenko说道。

相关结果发表在《Oncotarget》杂志上,他们发现在6种分子中,柳皮提取物具有最显著的效用,而这一现象之前并没有被任何杂志报道。试验中,柳皮提取物能够使酵母的平均生活周期延长4.75倍,最长生活周期延长3.69倍。

如果该结果能够在酵母以外的其它生物中得到重复,那将会是一个了不起的发现。另外,在除了延缓衰老之外,这些化合物还能够阻止一些疾病,比如癌症的发生。其它分子分别提取自类叶升麻、缬草、西番莲、银杏以及芹菜。

研究者们称他们将会分成6个不同的项目进一步研究这些分子的效应以及背后的机理。

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    2017-01-10 闆锋旦
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    2016-08-19 1e0e6c35m09(暂无匿称)

    里面没一样是我爱吃的

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2070269, encodeId=695320e026959, content=<a href='/topic/show?id=db9562e5542' target=_blank style='color:#2F92EE;'>#植物提取物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62755, encryptionId=db9562e5542, topicName=植物提取物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=07f7192, createdName=waiwai3030, createdTime=Thu Apr 21 11:05:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1795326, encodeId=06ff1e9532602, content=<a href='/topic/show?id=248e1e1345b' target=_blank style='color:#2F92EE;'>#target#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17134, encryptionId=248e1e1345b, topicName=target)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8409354, createdName=闆锋旦, createdTime=Tue Jan 10 20:05:00 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932367, encodeId=5b3d193236e48, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Thu Sep 01 18:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100616, encodeId=ab661006169e, content=里面没一样是我爱吃的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4f31938406, createdName=1e0e6c35m09(暂无匿称), createdTime=Fri Aug 19 05:04:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745191, encodeId=c7661e451913f, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue Sep 06 02:05:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81398, encodeId=0d7181398c2, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81399, encodeId=188f81399c0, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81393, encodeId=3b5081393a6, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81394, encodeId=89d5813945c, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81395, encodeId=c85c813957a, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2070269, encodeId=695320e026959, content=<a href='/topic/show?id=db9562e5542' target=_blank style='color:#2F92EE;'>#植物提取物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62755, encryptionId=db9562e5542, topicName=植物提取物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=07f7192, createdName=waiwai3030, createdTime=Thu Apr 21 11:05:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1795326, encodeId=06ff1e9532602, content=<a href='/topic/show?id=248e1e1345b' target=_blank style='color:#2F92EE;'>#target#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17134, encryptionId=248e1e1345b, topicName=target)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8409354, createdName=闆锋旦, createdTime=Tue Jan 10 20:05:00 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932367, encodeId=5b3d193236e48, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Thu Sep 01 18:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100616, encodeId=ab661006169e, content=里面没一样是我爱吃的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4f31938406, createdName=1e0e6c35m09(暂无匿称), createdTime=Fri Aug 19 05:04:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745191, encodeId=c7661e451913f, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue Sep 06 02:05:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81398, encodeId=0d7181398c2, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81399, encodeId=188f81399c0, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81393, encodeId=3b5081393a6, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81394, encodeId=89d5813945c, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81395, encodeId=c85c813957a, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=)]
    2016-04-23 忠诚向上

    好好看看学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2070269, encodeId=695320e026959, content=<a href='/topic/show?id=db9562e5542' target=_blank style='color:#2F92EE;'>#植物提取物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62755, encryptionId=db9562e5542, topicName=植物提取物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=07f7192, createdName=waiwai3030, createdTime=Thu Apr 21 11:05:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1795326, encodeId=06ff1e9532602, content=<a href='/topic/show?id=248e1e1345b' target=_blank style='color:#2F92EE;'>#target#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17134, encryptionId=248e1e1345b, topicName=target)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8409354, createdName=闆锋旦, createdTime=Tue Jan 10 20:05:00 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932367, encodeId=5b3d193236e48, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Thu Sep 01 18:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100616, encodeId=ab661006169e, content=里面没一样是我爱吃的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4f31938406, createdName=1e0e6c35m09(暂无匿称), createdTime=Fri Aug 19 05:04:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745191, encodeId=c7661e451913f, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue Sep 06 02:05:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81398, encodeId=0d7181398c2, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81399, encodeId=188f81399c0, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81393, encodeId=3b5081393a6, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81394, encodeId=89d5813945c, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81395, encodeId=c85c813957a, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=)]
    2016-04-23 忠诚向上

    好好看看学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2070269, encodeId=695320e026959, content=<a href='/topic/show?id=db9562e5542' target=_blank style='color:#2F92EE;'>#植物提取物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62755, encryptionId=db9562e5542, topicName=植物提取物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=07f7192, createdName=waiwai3030, createdTime=Thu Apr 21 11:05:00 CST 2016, time=2016-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1795326, encodeId=06ff1e9532602, content=<a href='/topic/show?id=248e1e1345b' target=_blank style='color:#2F92EE;'>#target#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17134, encryptionId=248e1e1345b, topicName=target)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8409354, createdName=闆锋旦, createdTime=Tue Jan 10 20:05:00 CST 2017, time=2017-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932367, encodeId=5b3d193236e48, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Thu Sep 01 18:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100616, encodeId=ab661006169e, content=里面没一样是我爱吃的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4f31938406, createdName=1e0e6c35m09(暂无匿称), createdTime=Fri Aug 19 05:04:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745191, encodeId=c7661e451913f, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Tue Sep 06 02:05:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81398, encodeId=0d7181398c2, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81399, encodeId=188f81399c0, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:15:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81393, encodeId=3b5081393a6, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81394, encodeId=89d5813945c, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=81395, encodeId=c85c813957a, content=好好看看学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Apr 23 07:14:00 CST 2016, time=2016-04-23, status=1, ipAttribution=)]
    2016-04-23 忠诚向上

    好好看看学习

    0

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    2016-04-23 忠诚向上

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