Heart:二尖瓣脱垂是开角型青光眼的显著预测因素

2014-12-16 小田 译 医学论坛网

台湾学者的一项基于人群的回顾性队列研究表明,既往存在二尖瓣脱垂是罹患开角型青光眼的显著预测因素。相关论文12月11日在线发表于《心脏》(Heart)杂志。 研究者们随机选取了纵向健康保险数据库中的1 073 891个样本,对其随访13年,其中倾向性评分相匹配的有和无二尖瓣脱垂患者数分别为21 677例和86 708例,作为对照。利用Cox比例风险模型进行分析和校正多个并病,以评估二尖瓣脱

台湾学者的一项基于人群的回顾性队列研究表明,既往存在二尖瓣脱垂是罹患开角型青光眼显著预测因素。相关论文12月11日在线发表于《心脏》(Heart)杂志。


研究者们随机选取了纵向健康保险数据库中的1 073 891个样本,对其随访13年,其中倾向性评分相匹配的有和无二尖瓣脱垂患者数分别为21 677例和86 708例,作为对照。利用Cox比例风险模型进行分析和校正多个并病,以评估二尖瓣脱垂患者的开角型青光眼的校正危险比(HR)。

结果显示,无二尖瓣脱垂组和二尖瓣脱垂组的开角型青光眼发生率分别为10.17和16.05每10 000人-年。二尖瓣脱垂组的开角型青光眼校正HR为1.88。在二尖瓣脱垂患者的4个分层的年龄组中,开角型青光眼风险也显著增加。Kaplan–Meier分析显示,与对照组相比,随访期间二尖瓣脱垂组的开角型青光眼发生率更高(P<0.001)。

原始出处:

Shuo Ju Chiang1,2, Masao Daimon3, Li Hsuan Wang4,5, Ming-Jui Hung6, Nen Chung Chang1,2, Hsiu Chen Lin7,8.Association between mitral valve prolapse and open-angle glaucoma.Heart doi:10.1136/heartjnl-2014-306198



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    2014-12-18 智智灵药
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    2014-12-18 wwzzly
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