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JCEM：天芪降糖胶囊减慢糖尿病患者糖耐量减退

2014-03-24 MedSci MedSci原创

天芪天芪降糖胶囊糖尿病
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最近一项多中心临床试验表明，中药复方天芪降糖胶囊可能具有抑制糖耐量异常的作用。在这项研究中，共420例糖耐量受损（impaired glucose tolerance，IGT）患者被随机分为天芪降糖胶囊组和安慰剂组，共治疗12个月。每3个月进行口服糖耐量测试，同时，所有患者均受到相同的生活方式教育。主要终点为最终IGT转换为II型糖尿病的比例。研究发现，在整个12个月试验中，天芪降糖胶囊湘鄂赣18

最近一项多中心临床试验表明，中药复方天芪降糖胶囊可能具有抑制糖耐量异常的作用。在这项研究中，共420例糖耐量受损（impaired glucose tolerance，IGT）患者被随机分为天芪降糖胶囊组和安慰剂组，共治疗12个月。每3个月进行口服糖耐量测试，同时，所有患者均受到相同的生活方式教育。主要终点为最终IGT转换为II型糖尿病的比例。研究发现，在整个12个月试验中，天芪降糖胶囊湘鄂赣18.18%的人群转换为II型糖尿病，而安慰剂组高达29.32%，两组有显著性差异(p=0.01)。试验结束时，两组患者糖耐量正常比例分别为63.13%和46.60%，COX回归分析显示，天芪降糖胶囊比安慰剂降低IGT向糖尿病转换的风险32.1%。本研究最终发表在JCEM上。


原始出处：
Lian F, Li G, Chen X, Wang X, Piao C, Wang J, Hong Y, Ba Z, Wu S, Zhou X, Lang J, Liu Y, Zhang R, Hao J, Zhu Z, Li H, Fang Liu H, Cao A, Yan Z, An Y, Bai Y, Wang Q, Zhen Z, Yu C, Wang CZ, Yuan CS, Tong X.Chinese herbal medicine tianqi reduces progression from impaired glucose tolerance to diabetes: a double-blind, randomized, placebo-controlled, multicenter trial. J Clin Endocrinol Metab. 2014 Feb;99(2):648-55 

 小知识：天芪降糖胶囊
成分：黄芪、天花粉、女贞子、石斛、人参、地骨皮、黄连（酒蒸）、山茱萸、墨旱莲、五倍子。
功能主治：益气养阴、清热生津。
用于2型糖尿病气阴两虚证，症见：倦怠乏力，口渴喜饮，五心烦热，自汗，盗汗，气短懒言，心悸失眠。
用法用量口服。一次5粒，一日3次，8周为一疗程，或遵医嘱。

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    2014-05-08 achengzhao

    #JCE#

    0

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    2014-05-01 smallant2015

    #JCEM#

    0

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    2014-03-28 lovetcm

    中药有前途的

    0

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    2014-03-26 xue8604

    #糖尿病患者#

    0

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    2014-03-26 fengxx

    #糖耐量#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2062849, encodeId=143f2062849d7, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu May 08 10:20:00 CST 2014, time=2014-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1777468, encodeId=6a751e774682f, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Thu May 01 11:20:00 CST 2014, time=2014-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8709, encodeId=81ca8e09bf, content=中药有前途的, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Fri Mar 28 12:26:00 CST 2014, time=2014-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473774, encodeId=552414e37741d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Wed Mar 26 13:20:00 CST 2014, time=2014-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500563, encodeId=820f15005639e, content=<a href='/topic/show?id=b2cbe6849b2' target=_blank style='color:#2F92EE;'>#糖耐量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76849, encryptionId=b2cbe6849b2, topicName=糖耐量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0e659435909, createdName=fengxx, createdTime=Wed Mar 26 13:20:00 CST 2014, time=2014-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8644, encodeId=f69d864413, content=中药研究还真牛了, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=60.55.40.34, createdTime=Mon Mar 24 22:33:00 CST 2014, time=2014-03-24, status=1, ipAttribution=)]
    2014-03-24 60.55.40.34

    中药研究还真牛了

    0