J Cereb Blood Flow Metab:预测急性脑卒中缺血再灌注后出血之利器——再灌注治疗后ASL脑血流高灌注表现与出血相关

2017-07-10 shaosai MedSci原创

对于急性脑卒中患者再灌注治疗后出血的早期检测是至关重要的,从而对急性脑卒中再灌注治疗后的早期干预是非常有指导意义的。研究人员通过利用ASL对比急性脑卒中缺血再灌注治疗后出血的危险性,表明ASL可作为梗死后出血的可靠标志。

对于急性脑卒中患者再灌注治疗后出血的早期检测是至关重要的,从而对急性脑卒中再灌注治疗后的早期干预是非常有指导意义的。研究人员通过利用ASL对比急性脑卒中缺血再灌注治疗后出血的危险性,表明ASL可作为梗死后出血的可靠标志。

研究人员通过脉冲动脉自旋标记(ASL)灌注MRI和123I-碘安非他明单光子发射计算机断层技术(123I-SPECT)扫描来评估术后出血性与再灌注治后高灌注之间的关系。

研究结果发现,在急性脑卒中并经再灌注治疗的患者,与非出血组相比,出血组中溶栓后或血管内介入的病变区的脑血流量明显升高。 在再灌注术后,局灶性高灌注(同侧对侧比> 1.5)与再灌注术后出血相关(OR=9.3; 95%CI:1.4-64.0)。

本研究结果表明,再灌注术后患者ASL超灌注现象可能作为梗死后出血的可靠标志。

原始出处:

Okazaki S , Yamagami H, Yoshimoto T , Cerebral hyperperfusion on arterial spin labeling MRI after reperfusion therapy is related to hemorrhagic transformation. J Cereb Blood Flow Metab. 2017. DOI: 10.1177/0271678X17718099

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    2018-05-26 一闲
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    2018-01-28 guojianrong
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    2017-07-12 lq1771
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    2017-07-11 shaosai

    好好学习,涨知识

    0

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