J Investig Clin Dent:益生菌辅助应用是否有益于牙周治疗效果

2018-04-05 MedSci MedSci原创

本研究旨在评估益生菌作为治疗慢性牙周炎(CP)中洁治和根面平整(SRP)的辅助效果。这项研究的焦点问题是:与安慰剂/无治疗组相比,益生菌的辅助使用可以在治疗CP时产生更好的临床牙周结果?电子和手册文献检索2017年12月前以下数据库收录的相关文章:MEDLINE,EMBASE,Cochrane对照试验中心注册和Cochrane口腔健康组试验注册。计算加权平均差异(WMD)和95%置信区间(CI)。

本研究旨在评估益生菌作为治疗慢性牙周炎(CP)中洁治和根面平整(SRP)的辅助效果。这项研究的焦点问题是:与安慰剂/无治疗组相比,益生菌的辅助使用可以在治疗CP时产生更好的临床牙周结果?

电子和手册文献检索2017年12月前以下数据库收录的相关文章:MEDLINE,EMBASE,Cochrane对照试验中心注册和Cochrane口腔健康组试验注册。计算加权平均差异(WMD)和95%置信区间(CI)。

结果共纳入了七项临床研究。四项研究表明在减少牙周探诊深度(PPD)和临床附着水平(CAL)获得方面有额外的益处,而三项研究显示益生菌和SRP/安慰剂之间的临床牙周结果相当。研究发现PPD降低和CAL增益存在明显的异质性。随访时,益生菌与安慰剂/SRP之间的CAL增加的整体平均差异明显(WMD = 1.41,95%CI = 0.15-2.67,P = .028)。

综上所述,该研究结果表明,辅助益生菌使用可以在CP中获得额外的益处。尽管如此,还需要进一步开展高质量的微生物学结果随机临床试验,以获得这方面的有力结论。

原始出处:

Ikram S, Hassan N, et al., Systematic review and meta-analysis of double-blind, placebo-controlled, randomized clinical trials using probiotics in chronic periodontitis. J Investig Clin Dent. 2018 Mar 31:e12338. doi: 10.1111/jicd.12338.

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    2018-04-07 liuyong2982
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    2018-04-05 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2018-04-05 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-04-05 虈亣靌

    优质资源.共同学习

    0

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