BMC Oral Health:舒张压升高与病理性的牙周袋有关

2015-05-07 MedSci MedSci原创

BMC Oral Health:舒张压升高与病理性的牙周袋有关众所周知,肥胖是心血管疾病(CVD)的危险因素,而且肥胖还与成人慢性牙周炎有关。本次横断面研究的目的是为了调查在肥胖青少年人群中,病理性牙周袋是否与血压升高有关,以及是否是CVD的危险因素。研究纳入了75名肥胖者,年龄在12至18岁,平均年龄为14.5岁。研究对象完成关于健康和社会人口学问题的调查问卷。临床检查包括可见菌斑指数(VPI

BMC Oral Health:舒张压升高与病理性的牙周袋有关




众所周知,肥胖是心血管疾病(CVD)的危险因素,而且肥胖还与成人慢性牙周炎有关。本次横断面研究的目的是为了调查在肥胖青少年人群中,病理性牙周袋是否与血压升高有关,以及是否是CVD的危险因素。

研究纳入了75名肥胖者,年龄在12至18岁,平均年龄为14.5岁。研究对象完成关于健康和社会人口学问题的调查问卷。临床检查包括可见菌斑指数(VPI %),探针出血位点数(BOP %)以及病理性牙周袋超过4毫米(PD>4㎜)的病理性牙周袋位点数。收集血清并分析测量每位研究对象的收缩压和舒张压,并记录。

结果发现,与无病理性牙周袋的研究对象(PD < 4 mm; n = 61)相比,存在病理性牙周袋的青少年(PD ≥ 4 mm; n = 14) ),其血清中BOP>25%的位点明显增多(p=0.002),舒张压明显升高(P = 0.008),白介素(IL)-6的水平明显升高(P < 0.001),瘦素的水平明显升高(P = 0.018),单核细胞趋化蛋白-1(MCP-1)明显升高(P = 0.049),促甲状腺激素(TSH)也明显升高(P = 0.004)。双变量线性回归分析表明,PD≥4㎜((P = 0.008)和收缩压 (P < 0.001) 均与舒张压显著相关。多元线性回归分析中校正了BMI-sds,年龄,性别,母亲出生地,BOP>25%,IL-6, IL-8, Leptin, MCP-1, TSH 以及总胆固醇之后,PD≥4㎜与舒张压之间仍显著相关。

总之,本研究结果显示,肥胖青少年病理性牙周袋与舒张压之间具有关联。而且该关联并不受其他的心血管疾病危险因素或牙周病的影响。本研究结果呼吁儿科牙医需与内科医师合作共同预防肥胖及相关疾病的发生发展。

原始出处:
Cecilia C Zeigler, Biniyam Wondimu, Claude Marcus, Thomas Modéer.Pathological Periodontal Pockets Are Associated With Raised Diastolic Blood Pressure in Obese Adolescents.BMC Oral Health. 2015;15(41) 

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time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450410, encodeId=484514504109c, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478756, encodeId=d69a14e875628, content=<a href='/topic/show?id=0ab56e545e5' target=_blank style='color:#2F92EE;'>#牙周袋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67545, encryptionId=0ab56e545e5, topicName=牙周袋)], attachment=null, authenticateStatus=null, 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createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

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  2. 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createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
    2016-02-29 小几洁
  3. 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    2015-07-20 shizhenshan
  4. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 29 09:46:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861012, encodeId=8c3d1861012a7, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon Jul 20 01:46:00 CST 2015, time=2015-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974604, encodeId=832c19e46048a, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sun Jan 03 17:46:00 CST 2016, time=2016-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323087, encodeId=4eb8132308ef1, content=<a href='/topic/show?id=80ca865895e' target=_blank style='color:#2F92EE;'>#舒张压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86589, encryptionId=80ca865895e, topicName=舒张压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450410, encodeId=484514504109c, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478756, encodeId=d69a14e875628, content=<a href='/topic/show?id=0ab56e545e5' target=_blank style='color:#2F92EE;'>#牙周袋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67545, encryptionId=0ab56e545e5, topicName=牙周袋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=251b7453350, createdName=ms3153534357578991, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621537, encodeId=c38c162153e7d, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22882, encodeId=0fc02288290, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=125338, encodeId=90ef125338c4, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:26:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020167, encodeId=d3b1202016e5b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 29 09:46:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861012, encodeId=8c3d1861012a7, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon Jul 20 01:46:00 CST 2015, time=2015-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974604, encodeId=832c19e46048a, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sun Jan 03 17:46:00 CST 2016, time=2016-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323087, encodeId=4eb8132308ef1, content=<a href='/topic/show?id=80ca865895e' target=_blank style='color:#2F92EE;'>#舒张压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86589, encryptionId=80ca865895e, topicName=舒张压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450410, encodeId=484514504109c, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478756, encodeId=d69a14e875628, content=<a href='/topic/show?id=0ab56e545e5' target=_blank style='color:#2F92EE;'>#牙周袋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67545, encryptionId=0ab56e545e5, topicName=牙周袋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=251b7453350, createdName=ms3153534357578991, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621537, encodeId=c38c162153e7d, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22882, encodeId=0fc02288290, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=125338, encodeId=90ef125338c4, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:26:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020167, encodeId=d3b1202016e5b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Feb 29 09:46:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861012, encodeId=8c3d1861012a7, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Mon Jul 20 01:46:00 CST 2015, time=2015-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974604, encodeId=832c19e46048a, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sun Jan 03 17:46:00 CST 2016, time=2016-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323087, encodeId=4eb8132308ef1, content=<a href='/topic/show?id=80ca865895e' target=_blank style='color:#2F92EE;'>#舒张压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86589, encryptionId=80ca865895e, topicName=舒张压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450410, encodeId=484514504109c, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478756, encodeId=d69a14e875628, content=<a href='/topic/show?id=0ab56e545e5' target=_blank style='color:#2F92EE;'>#牙周袋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67545, encryptionId=0ab56e545e5, topicName=牙周袋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=251b7453350, createdName=ms3153534357578991, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621537, encodeId=c38c162153e7d, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22882, encodeId=0fc02288290, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
    2015-05-09 heli0118
  7. 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time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450410, encodeId=484514504109c, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478756, encodeId=d69a14e875628, content=<a href='/topic/show?id=0ab56e545e5' target=_blank style='color:#2F92EE;'>#牙周袋#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67545, encryptionId=0ab56e545e5, topicName=牙周袋)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=251b7453350, createdName=ms3153534357578991, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621537, encodeId=c38c162153e7d, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sat May 09 07:46:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22882, encodeId=0fc02288290, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=161, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu May 07 21:03:00 CST 2015, time=2015-05-07, status=1, ipAttribution=)]
  8. 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    2015-05-07 huaxipanxing

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