2012 BCSH:血栓性血小板减少性紫癜及其他血栓性微血管病变指南
2012-05-25 英国血液学标准委员会 Br J Haematol. 2012 May 25. [Epub ahead of print]
2012 BCSH:血栓性血小板减少性紫癜及其他血栓性微血管病变指南
Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies
2012-05-25
The guideline group was selected to be representative of UKbasedmedical experts. MEDLINE and EMBASE weresearched systematically for publications in English, using thekeywords: thrombotic thrombocytopenia purpura (TTP), ADAMTS13,plasma exchange (PEX) and relevant key wordsrelated to the subsections of this guideline. The writing groupproduced the draft guideline, which was subsequently revisedby consensus by members of the Haemostasis and ThrombosisTask Force of the BCSH. The guideline was then reviewedby a sounding board of British haematologists, the BCSH andthe British Society for Haematology Committee and commentsincorporated where appropriate. The ‘GRADE’ systemwas used to quote levels and grades of evidence, details ofwhich can be found at http://www.bcshguidelines.com.The objective of this guideline is to provide healthcareprofessionals with clear, up-to-date, and practical guidanceon the management of TTP and related thrombotic microangiopathies,defined by thrombocytopenia, microangiopathichaemolytic anaemia (MAHA) and small vessel thrombosis.
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