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MiR-210-3p accelerates tumor-relevant cell functions of endometrial carcinoma by repressing RUNX1T1

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

Background: Biological mechanism of miR-210-3p in endometrial carcinoma (EC) remains unclear. Here, our purpose is to study effects of miR-210-3p on m......

JIF:0.0

The kidney-expressed transcription factor ZKSCAN3 is dispensable for autophagy transcriptional regulation and AKI progression in mouse

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

Acute kidney injury (AKI) is a common clinical disease that can cause serious harm to the kidneys, but it has no effective treatment till now. The mod......

JIF:0.0

MiRNA-144-5p down-modulates CDCA3 to regulate proliferation and apoptosis of lung adenocarcinoma cells

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

Background: Lung adenocarcinoma (LUAD) belongs to non-small cell lung cancer. In addition to surgical resec-tion, chemotherapy and radiotherapy cause ......

JIF:0.0

In vitro and in silico analysis of a E559K mutation on cartilage oligomeric matrix protein

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 824 ()

Pseudoachondroplasia (PSACH) is known as an autosomal dominant disorder associated with mutations in the gene of cartilage oligomeric matrix protein (......

JIF:0.0

EZH2 affects malignant progression and DNA damage repair of lung adenocarcinoma cells by regulating RAI2 expression

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

Background: Lung adenocarcinoma (LUAD) is featured in high morbidity and mortality. Aberrant activation of the histone methyltransferase EZH2 has clos......

JIF:0.0

Construction and evaluation of a prognostic risk assessment model of gastric cancer by using hypoxia features

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

In this study, mRNA expression of gastric cancer tissue and clinical data of patients in TCGA-STAD dataset were used, together with the hypoxia-relate......

JIF:0.0

Dysregulation of miR-204-5p/APLN axis affects malignant progression and cell stemness of esophageal cancer

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2022; 825 ()

Objective: This study attempted to investigate the mechanism of miR-204-5p and its downstream gene in regu-lating bio-functions of esophageal cancer (......

JIF:0.0

Aurora kinases and DNA damage response

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2020; 821 ()

It is well established that Aurora kinases perform critical functions during mitosis. It has become increasingly clear that the Aurora kinases also pe......

Induction of proliferative and mutagenic activity by benzo(a)pyrene in PC-3 cells via JAK2/STAT3 pathway

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2020; 821 ()

Environmental carcinogen benzo(a)pyrene (BaP) is a representative compound of polycyclic aromatic hydro-carbons (PAHs). BaP is strongly associated wit......

Is level of acetylation directly correlated to radiation sensitivity of cancer cell?

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2019; 813 ()

It is known that histone deacetylase inhibitors (HDACis) can modify acetylation of tumor cells and affect radiation sensitivity, or, radiosensitivity.......

JIF:2.01

High concentration of sugars is genotoxic to folate-deficient cells

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2019; 814 ()

Patients with type 2 diabetes mellitus (T2DM) are associated with an elevated, but poorly understood baseline of genomic instability (GIN). Expert pan......

JIF:2.01

Strategies for identification of mutations induced by carbon-ion beam irradiation in Arabidopsis thaliana by whole genome re-sequencing

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2018; 807 ()

Heavy-ion beam irradiation is a powerful physical mutagen that has been used to create numerous mutant materials in plants. These materials are an ess......

JIF:2.01

Drosophila bendless catalyzes K63-linked polyubiquitination and is involved in the response to DNA damage

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2018; 808 ()

In this study, we report the identification and functional characterization of the Drosophila ben/ubc13 gene, encoding a unique ubiquitin-conjugating ......

JIF:2.01

Identification of nonsynonymous TP53 mutations in hydatidiform moles

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2018; 809 ()

Hydatidiform mole (HM), an unusual pregnancy with pure or predominant paternal genetic contribution, is the most common form of gestational trophoblas......

JIF:2.01

The first (6-4) photolyase with DNA damage repair activity from the Antarctic microalga Chlamydomonas sp ICE-L

期刊: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2018; 809 ()

The psychrophilic microalga, Chlamydomonas sp. ICE-L, isolated from floating ice in the Antarctic, one of the most highly UV exposed ecosystems on Ear......

JIF:2.01

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