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Significant ketoacidosis at autopsy: a single-centre systematic review

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (3)

Aim To examine the value of vitreous beta-hydroxybutyrate and serum acetone in the investigation of sudden unexpected death. Methods Coroners' autopsy......

Industry payments to pathologists in the USA between 2013 and 2021

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (8)

Although proper physician-industry financial relationships are essential for improving patient care, they can also cause potential conflicts of intere......

Prevalence of elevated serum concentrations of biotin in patients from South East England, Korea, Singapore and Thailand and risk of immunoassay interference

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (9)

Biotin interference in immunoassays using biotin-streptavidin binding technology is well recognised by clinical laboratories, though the prevalence of......

Comprehensive characterisation of acinar cystic transformation of the pancreas: a systematic review

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; ()

Aims Acinar cystic transformation (ACT) of the pancreas is a rare pancreatic cystic lesion. Owing to its rarity, comprehensive histomolecular characte......

Assessment of large droplet fat in frozen sections of donor liver biopsies: utility and interobserver variability of the newly described Banff method compared to a simplified Average of Fields method

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; ()

Aims There is great variability in the assessment and reporting of fat in frozen sections of donor liver biopsies. The Banff Working Group has propose......

Putrefaction in the pandemic: a comparative study of the frequency of advanced decomposition change in coronial autopsies since the start of the COVID-19 pandemic

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (2)

Aims The aim of this study is to evaluate whether there has been a significant change in the frequency of markedly decomposed bodies having coronial a......

BAP1-deficient meningioma presenting with trabecular architecture and cytokeratin expression: a report of two cases and review of the literature

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (5)

Aims BRCA (BReast CAncer gene)-associated protein 1 (BAP1), encoded by the BAP1 gene, a tumour suppressor that is lost in several cancers. Importantly......

Mid-regional proadrenomedullin (MR-proADM), C-reactive protein (CRP) and other biomarkers in the early identification of disease progression in patients with COVID-19 in the acute NHS setting

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (6)

Aims There is a lack of biomarkers validated for assessing clinical deterioration in patients with COVID-19 on presentation to secondary or tertiary c......

MMR profile and microsatellite instability status in colorectal mucinous adenocarcinoma with synchronous metastasis: a new clue for the clinical practice

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (7)

Aims Mucinous adenocarcinoma (MA) is associated with a high frequency of microsatellite instability (MSI). In the metastatic setting, it is crucial to......

One-step genotyping of α-thalassaemia by multiplex symmetric PCR melting curve

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (9)

Aims Alpha-thalassaemia is one of the most common monogenic disorders worldwide. Due to high guanine-cytosine (GC) content and high mutation diversity......

Evaluation of CSF kappa free light chains for the diagnosis of multiple sclerosis (MS): a comparison with oligoclonal bands (OCB) detection via isoelectric focusing (IEF) coupled with immunoblotting

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (5)

This study was done to evaluate the diagnostic accuracy of cerebrospinal fluid kappa free light chain (KFLC) for diagnosis of multiple sclerosis, agai......

Best practice for LDL-cholesterol: when and how to calculate

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (3)

The lipid profile is important in the risk assessment for cardiovascular disease. The lipid profile includes total cholesterol, high-density lipoprote......

In-house homologous recombination deficiency testing in ovarian cancer: a multi-institutional Italian pilot study

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; ()

AimsPoly (ADP-ribose) polymerase (PARP) inhibitors (PARPIs) represent a standard of care for the clinical management of high-grade serous ovarian canc......

Cost analysis of archives in the pathology laboratories: from safety to management

期刊: JOURNAL OF CLINICAL PATHOLOGY, 2023; 76 (10)

ContextDespite the reluctance to invest and the challenging estimation of necessary supporting costs, optimising the archives seems to be one of the h......

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