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Gene Manipulation Protocols in Autophagy

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Macroautophagy (referred to as autophagy hereafter) is a highly conserved catabolic process in eukaryotic cells. Autophagy is essential for cellular h......

Mechanisms of Selective Autophagy

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is a lysosome-dependent degradation process. During autophagy, cytoplasmic components are sequestered and catabolized to supply nutrition an......

Autophagic Flux Detection: Significance and Methods Involved

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Macroautophagy is an important biological process in eukaryotic cells by which longevity proteins, misfolded proteins, and damaged organelles are degr......

Cell Models in Autophagy Research

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is highly conserved in organisms ranging from yeast to humans. C. elegans, D. melanogaster, zebrafish, and mice have been extensively used t......

MicroRNAs Regulating Autophagy in Neurodegeneration

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Social and economic impacts of neurodegenerative diseases (NDs) become more prominent in our constantly aging population. Currently, due to the lack o......

Autophagosome Trafficking

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is a major intracellular degradation/recycling system that ubiquitously exists in eukaryotic cells. Autophagy contributes to the turnover of......

Autophagy in Drosophila and Zebrafish

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is a highly conserved cellular process that delivers cellular contents to the lysosome for degradation. It not only serves as a bulk degrada......

Screening for Genes Involved in Autophagy

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is an important intracellular lysosomal degradation process in cells, which is highly conserved from yeast to mammals. The process of autoph......

Bioinformatics Technologies in Autophagy Research

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is an important and dynamic biological process, and provides an ideal application scenario for bioinformatics to develop new data resources,......

Chemical Autophagy Regulators

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is a catabolic process that removes aggregated proteins and damaged organelles via lysosomal degradation. Increasing evidence suggests that ......

Similarities and Differences of Autophagy in Mammals, Plants, and Microbes

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy, a highly conserved metabolic process in eukaryotes, is a widespread degradation/recycling system. However, there are significant difference......

The Fusion Between Autophagic Vesicles and Lysosomes

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

The autophagosome delivers engulfed substrates to the lysosome for degradation via membrane fusion between the autophagosome and the lysosome. The pro......

Proteomics and Autophagy Research

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Autophagy is an evolutionarily conserved intracellular degradation process. Autophagy is closely involved in human health and diseases. In recent year......

Phagophore Closure

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Phagophore closure is a critical step during macroautophagy. However, the proteins and mechanisms to regulate this step have been elusive for a long t......

Biomarkers of Autophagy

期刊: AUTOPHAGY: BIOLOGY AND DISEASES: TECHNOLOGY AND METHODOLOGY, 2021; 1208 ()

Biomarkers (short for biological markers) are biological measures of a biological state. Autophagy biomarkers play an important role as an indicator o......

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