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Dementia in China: epidemiology, clinical management, and research advances

期刊: LANCET NEUROLOGY, 2020; 19 (1)

China has the largest population of patients with dementia in the world, imposing a heavy burden on the public and health care systems. More than 100 ......

Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

期刊: LANCET NEUROLOGY, 2020; 19 (2)

Background Previous randomised trials have shown an overwhelming benefit of mechanical thrombectomy for treating patients with stroke caused by large ......

The characterisation of subjective cognitive decline

期刊: LANCET NEUROLOGY, 2020; 19 (3)

A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired ......

Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial

期刊: LANCET NEUROLOGY, 2020; 19 (5)

Background Azathioprine is used as a first-line treatment to prevent relapses of neuromyelitis optica spectrum disorder (NMOSD). Tocilizumab has been ......

Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre, randomised, placebo-controlled, phase 2 trial

期刊: LANCET NEUROLOGY, 2020; 19 (12)

Background Despite intracerebral haemorrhage causing 5% of deaths worldwide, few evidence-based therapeutic strategies other than stroke unit care exi......

Integrated and patient-centred management of Parkinson's disease: a network model for reshaping chronic neurological care

期刊: LANCET NEUROLOGY, 2020; 19 (7)

Chronic neurological diseases are the leading cause of disability globally. Yet, our health-care systems are not designed to meet the needs of many pa......

Potential human transmission of amyloid beta pathology: surveillance and risks

期刊: LANCET NEUROLOGY, 2020; 19 (10)

Studies in experimental animals show transmissibility of amyloidogenic proteins associated with prion diseases, Alzheimer's disease, Parkinson's disea......

Neuroinflammation in intracerebral haemorrhage: immunotherapies with potential for translation

期刊: LANCET NEUROLOGY, 2020; 19 (12)

Intracerebral haemorrhage is inadequately controlled by current treatments, requiring new solutions to improve the prognosis. Following the primary in......

Clinical characteristics and outcomes in patients with traumatic brain injury in China: a prospective, multicentre, longitudinal, observational study

期刊: LANCET NEUROLOGY, 2020; 19 (8)

Summary Background Large-scale studies are required to better characterise traumatic brain injury (TBI) and to identify the most effective treatment a......

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