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BDNF Val66Met Polymorphism: Suggested Genetic Involvement in Some Children with Learning Disorder

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (1)

Brain-derived neurotrophic factor (BDNF) plays an essential role in neuronal survival, especially in areas responsible for memory and learning. The BD......

Spreading of Tau Protein Does Not Depend on Aggregation Propensity

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (9-10)

The stereotypical progression of Tau pathology during Alzheimer disease has been attributed to trans-neuronal spreading of misfolded Tau proteins, fol......

Treadmill Exercise Improves Behavioral and Neurobiological Alterations in Restraint-Stressed Rats

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (9-10)

Stress is a state that is known to impact an organism's physiological and psychological balance as well as the morphology and functionality of certain......

Neuroprotective Efficacy of Fisetin Against VPA-Induced Autistic Neurobehavioral Alterations by Targeting Dysregulated Redox Homeostasis

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (6)

Autism is a neurodevelopmental condition, and it's associated pathophysiology, viz., oxidative stress and altered cellular homeostasis, has been exten......

Early Alterations of PACAP and VIP Expression in the Female Rat Brain Following Spinal Cord Injury

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; ()

Previous evidence shows that rapid changes occur in the brain following spinal cord injury (SCI). Here, we interrogated the expression of the neuropep......

Understanding the Molecular Regulation of Serotonin Receptor 5-HTR1B-β-Arrestin1 Complex in Stress and Anxiety Disorders

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (7-8)

The serotonin receptor subtype 5-HTR1B is widely distributed in the brain with an important role in various behavioral implications including neurolog......

Transcriptomics Meta-Analysis Reveals Phagosome and Innate Immune System Dysfunction as Potential Mechanisms in the Cortex of Alzheimer's Disease Mouse Strains

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (9-10)

Immune-related pathways can affect the immune system directly, such as the chemokine signaling pathway, or indirectly, such as the phagosome pathway. ......

Association of Telomere Length with Cognitive Impairment

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (6)

Telomere attrition is attributed to Alzheimer's disease (AD), major depressive disorder, stress levels, physical inactivity, short sleep duration, and......

Whole-Blood Metabolomics of a Rat Model of Repetitive Concussion

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (9-10)

Mild traumatic brain injury (mTBI) and repetitive mTBI (RmTBI) are silent epidemics, and so far, there is no objective diagnosis. The severity of the ......

Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (4-5)

Autism spectrum disorder (ASD) is a neurodevelopmental disability that causes social impairment, debilitated verbal or non -verbal conversation, and r......

A Novel Truncating Mutation in PAX1 Gene Causes Otofaciocervical Syndrome Without Immunodeficiency

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (11-12)

Otofaciocervical syndrome (OTFCS) is a rare genetic disorder of both autosomal recessive and autosomal dominant patterns of inheritance. It is caused ......

RNA Sequencing of Intraoperative Peritumoral Tissues Reveals Potential Pathways Involved in Glioma-Related Seizures

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (6)

Tumor-induced changes in the peritumoral neocortex play a crucial role in generation of seizures. This study aimed to investigate the molecular mechan......

BMP4, SGSH, and SLC11A2 are Predicted to Be Biomarkers of Aging Associated with Programmed Cell Death

期刊: JOURNAL OF MOLECULAR NEUROSCIENCE, 2023; 73 (9-10)

Most neurodegenerative diseases are exacerbated by aging, with symptoms often worsening over time. Programmed cell death (PCD) is a controlled cell su......

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