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High-mobility Group Box 1 Facilitates CD4 T Cell Self-aggregation Via Integrin and STAT3 Activation Before Homing

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (8)

Background: High-mobility group box 1 (HMGB1) is one of the delayed pro-inflammatory cytokines produced in the later stages of pathogenesis and plays ......

Potential of Electrical Neuromodulation for Inflammatory Bowel Disease

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (8)

Inflammatory bowel disease (IBD) is a common chronic inflammatory disease of the digestive tract that is often debilitating. It affects patients' qual......

Propagation of EBV-driven Lymphomatous Transformation of Peripheral Blood B Cells by Immunomodulators and Biologics Used in the Treatment of Inflammatory Bowel Disease

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (9)

Background: Immunomodulators and anti tumor-necrosis-alpha antibodies (anti-TNFs) have been implicated in increased risk of Epstein-Barr virus (EBV)-d......

Fungal Dysbiosis Aggravates Pouchitis in a Rat Model of Ileal Pouch Anal Anastomosis

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (12)

Background: Although the interaction between gut microbiota and pouchitis after ileal pouch anal anastomosis (IPAA) for ulcerative colitis (UC) has be......

Making Qualitative Intestinal Stricture Quantitative: Embracing Radiomics in IBD

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (5)

Quantifying intestinal fibrosis is an important but challenging issue in stricturing CD. With the advent of radiomics, MRE and CTE are highly minable ......

Fucose Ameliorate Intestinal Inflammation Through Modulating the Crosstalk Between Bile Acids and Gut Microbiota in a Chronic Colitis Murine Model

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (6)

Background: Recurrent intestinal inflammation is frequently associated with aberrant bile acid profiles and microbial community. Fucose exerts a prote......

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

期刊: INFLAMMATORY BOWEL DISEASES, 2020; 26 (6)

Very early onset inflammatory bowel disease (VEO-IBD) is defined as IBD presenting before 6 years of age. When compared with IBD diagnosed in older ch......

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