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The Combo radiotherapy treatment for high-risk grade 2 meningiomas: dose escalation and initial safety and efficacy analysis

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 161 (2)

Purpose The subgroup high-risk WHO grade 2 (hRG2) meningiomas may benefit from adjuvant radiation therapy (RT), but results are still suboptimal with ......

Re-irradiation for recurrent high-grade glioma: an analysis of prognostic factors for survival and predictors of radiation necrosis

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 163 (3)

PurposeRecurrent high-grade glioma (rHGG) is a heterogeneous population, and the ideal patient selection for re-irradiation (re-RT) has yet to be esta......

Retrospective non-inferiority study of stereotactic radiosurgery for more than ten brain metastases

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 163 (2)

AimThis study aimed to investigate the clinical benefits of stereotactic radiosurgery (SRS) in patients with > 10 brain metastases (BM) compared to......

Long-term neurocognitive function and quality of life after multimodal therapy in adult glioma patients: a prospective long-term follow-up

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 164 (2)

Purpose Multimodal therapies have significantly improved prognosis in glioma. However, in particular radiotherapy may induce long-term neurotoxicity c......

Residual diffusion-weighted imaging hyperintense signal in primary central nervous system lymphoma can predict early recurrence

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 165 (1)

BackgroundThe treatment response of primary central nervous system lymphomas (PCNSLs) is mainly evaluated using postcontrast T1-weighted imaging (T1WI......

RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 165 (3)

PurposeSpinal ependymoma (SE) is a rare tumor that is most commonly low-grade and tends to recur when complete tumor resection is not feasible. We inv......

Deep DNA sequencing of MGMT, TP53 and AGT in Mexican astrocytoma patients identifies an excess of genetic variants in women and a predictive biomarker

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 161 (1)

Purpose Astrocytomas are a type of malignant brain tumor with an unfavorable clinical course. The impact of AGT and MGMT somatic variants in the progn......

Surgeon experience in glioblastoma surgery of the elderly-a multicenter, retrospective cohort study

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 161 (3)

PurposeTo assess the impact of individual surgeon experience on overall survival (OS), extent of resection (EOR) and surgery-related morbidity in elde......

Metabolic delineation of IDH1 wild-type glioblastoma surgical anatomy: how to plan the tumor extent of resection

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 162 (2)

PurposeMagnetic resonance imaging (MRI) is the current standard for preoperative planning of glioblastoma (GBM) surgery. However, recent data on the u......

Incidence of clinically relevant psychiatric symptoms during glioblastoma treatment: an exploratory study

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 163 (1)

PurposeIn addition to neurological symptoms glioblastoma (GBM) patients can experience psychiatric complaints, which are often hard to recognize and d......

Volumetric hippocampal changes in glioblastoma: a biomarker for neuroplasticity?

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 163 (1)

PurposeThe pleiotropic effect of gliomas on the development of cognitive disorders and structural brain changes has garnered increasing interest in re......

Long-term follow up of patients with WHO grade 2 oligodendroglioma

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; ()

Purpose Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeleti......

A combined analysis of two prospective randomised studies exploring the impact of extended post-radiation temozolomide on survival outcomes in newly diagnosed glioblastoma

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; ()

PurposeThe optimal duration of post-radiation temozolomide in newly diagnosed glioblastoma remains unclear, with no published phase III randomised tri......

Hypofractionated stereotactic radiosurgery (HSRS) as a salvage treatment for brain metastases failing prior stereotactic radiosurgery (SRS)

期刊: JOURNAL OF NEURO-ONCOLOGY, 2023; 162 (1)

IntroductionVarious treatment options exist to salvage stereotactic radiosurgery (SRS) failures for brain metastases, including repeat SRS and hypofra......

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