期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 41 ()
Infections caused by antibiotic resistant bacteria are a major health concern throughout the world. It is well known that PFK-158 can enhance the anti......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 43 ()
Necroptosis is a form of programmed cell death that contributes to the pathophysiology of multiple diseases. Development of small-molecule anti-necrop......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 43 ()
Alzheimer's disease is a progressive neurodegenerative disease, and its incidence is expected to increase as the global population ages. Recent studie......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 40 ()
Five new alpha -pyrone derivatives, named penpolonin A-E (1-5), together with two known compounds (6-7) were acquired from the endophytic fungus Penic......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 43 ()
To explore natural-product-based insecticide candidates, and high value-added application of natural plants in agriculture, a series of twin compounds......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 43 ()
In the studies on dihydroxy intermediate synthesis, a serendipitous reaction of introducing nitro group from nitromethylene has been observed. Instead......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 40 ()
Altered glucose-6-phosphate dehydrogenase (G6PD) status is influential in many cellular pathophysiological processes and diseases, making G6PD a poten......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 40 ()
In this study, a series of sulfonamide compounds was designed and synthesized through the systematic optimization of the antibacterial agent sulfaphen......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 41 ()
Monoacylglycerol lipase (MAGL) is the major enzyme that catalyzes the hydrolysis of monoacylglycerols (MAGs). MAGL is responsible for degrading 2-arac......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 41 ()
Spinal cord injury (SCI) is a chronic disease causing motor and sensory loss in the affected individuals. The SCI has a huge impact on the lives of pa......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 46 ()
In recent years, combination therapy has gradually become one of the hot spots. As a new therapy strategy, we investigated the combination treatment o......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 47 ()
In order to discover new anticancer agents, 25 novel 2,4-diamino-5-methyleneaminopyrimidine derivatives were designed and synthesized based on our pre......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 48 ()
Five cyanine dyes (6a-e) with aza units were prepared by the reaction of pyridinum or quinolinium with suitable aldehydes. They present several remark......
期刊： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 44 ()
Nucleic acid sensing pathways play an important role in the innate immune system, protecting hosts against infections. However, a large body of eviden......
