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An evolutionary perspective on the interplays between hydrogen sulfide and oxygen in cellular functions

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 707 ()

The physiological effects of the endogenously generated hydrogen sulfide (H2S) have been extensively studied in recent years. This review summarized t......

Redox interactions-induced cardiac toxicity in cancer therapy

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 708 ()

Cancer patients undergoing radiotherapy, chemotherapy, or targeted cancer therapy are exposed to the risk of several side effects because of the heavy......

Bovine extracellular vesicles contaminate human extracellular vesicles produced in cell culture conditioned medium when 'exosome-depleted serum' is utilised

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 708 ()

Extracellular vesicles (EVs) are important intercellular communication messengers. Half of the published studies in the field are in vitro cell cultur......

PCSK9: Associated with cardiac diseases and their risk factors?

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 704 ()

PCSK9 plays a critical role in cholesterol metabolism via the PCSK9-LDLR axis. Liver-derived, circulating PCSK9 has become a novel drug target in lipi......

LncRNA AK087124/miR-224-5p/PTEN axis modulates endothelial cell injury in atherosclerosis through apoptosis and AKT signaling pathway

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 705 ()

Noncoding RNAs (ncRNAs) have been shown to play important roles in atherosclerosis-related endothelial cells dysfunction during atherosclerosis proces......

Unusual orthologs shed new light on the binding mechanism of ghrelin to its receptor GHSR1a

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 704 ()

The gastric peptide ghrelin has important functions in energy metabolism and cellular homeostasis by activating growth hormone secretagogue receptor t......

Exosome-shuttled miR-7162-3p from human umbilical cord derived mesenchymal stem cells repair endometrial stromal cell injury by restricting APOL6

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 707 ()

Background: Recent studies have shown that exosomes (Exos) derived from stem cells can be used as paracrine factors to regenerate cells and tissues vi......

miR-93 regulates liver tumor initiating cells expansion and predicts chemotherapeutic response of patients

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 703 ()

Tumor initiating cells (T-ICs) play an important role in tumorigenesis, progression, metastasis, recurrence and drug resistance, but the underlying me......

Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 702 ()

The antimetabolite 5-fluorouracil (5-FU) is a widely used chemotherapy regimen for the treatment of gastric cancer (GC). However, resistance to 5-FU r......

MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 704 ()

Micro-ribonucleic acids (miRNAs) are a class of conserved small non-coding RNAs (sncRNAs) that posttranscriptionally regulate their downstream target ......

Urinary metabolomic analysis to identify potential markers for the diagnosis of tuberculosis and latent tuberculosis

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 704 ()

Tuberculosis (TB) is a serious infectious disease with high infection and mortality rates. 5%-10% of the latent tuberculosis infections (LTBI) are lik......

Use Chou's 5-steps rule to study how Baicalin suppresses the malignant phenotypes and induces the apoptosis of colorectal cancer cells

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 705 ()

Baicalin is a traditional Chinese herb purified from the root of Scutellaria baicalensis Georgi. In this study, we further analyzed the molecular mech......

Oat polyphenol avenanthramide-2c confers protection from oxidative stress by regulating the Nrf2-ARE signaling pathway in PC12 cells

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 706 ()

Accumulating evidence has demonstrated that cellular antioxidant systems play essential roles in retarding oxidative stress-related diseases, such as ......

Characterization of the immune cell infiltration landscape in bladder cancer to aid immunotherapy

期刊: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 708 ()

The tumor microenvironment (TME) is composed mainly of tumor cells, tumorinfiltrating immune cells, and matrix components. Recent clinical studies hav......

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