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Subclassification of epithelioid sarcoma with potential therapeutic impact

期刊: JOURNAL OF PATHOLOGY, 2023; 260 (4)

Epithelioid sarcoma is a rare and aggressive mesenchymal tumour, the genetic hallmark of which is the loss of expression of SMARCB1, a key member of t......

CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea

期刊: JOURNAL OF PATHOLOGY, 2023; 260 (3)

Chemotherapy-induced diarrhea causes dehydration, debilitation, infection, and even death, but there are currently no Food and Drug Administration (FD......

Integrative analysis of transcriptomic and metabolomic profiles reveals abnormal phosphatidylinositol metabolism in follicles from endometriosis-associated infertility patients

期刊: JOURNAL OF PATHOLOGY, 2023; 260 (3)

Endometriosis is a common gynecological disorder that causes female infertility. Our recent research found that excessive oxidative stress in ovaries ......

Collagen VI promotes recovery from colitis by inducing lymphangiogenesis and drainage of inflammatory cells

期刊: JOURNAL OF PATHOLOGY, 2023; 260 (4)

Despite a number of studies providing evidence that the extracellular matrix (ECM) is an active player in the pathogenesis of intestinal inflammation,......

Spatial transcriptomics reveals heterogeneity of macrophages in the tumor microenvironment of granulomatous slack skin

期刊: JOURNAL OF PATHOLOGY, 2023; ()

Granulomatous slack skin (GSS) is an extremely rare subtype of cutaneous T-cell lymphoma accompanied by an abundant number of macrophages and is clini......

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