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Osthole Exerts Inhibitory Effects on Hypoxic Colon Cancer Cells via EIF2 alpha Phosphorylation-mediated Apoptosis and Regulation of HIF-1 alpha

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (2)

Hypoxic microenvironment and dysregulated endoplasmic reticulum stress/ unfolded protein response (UPR) system are considered important factors that p......

JIF:4.332

A Review of Traditional Chinese Medicine on Treatment of Diabetic Nephropathy and the Involved Mechanisms

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (7)

Diabetic nephropathy (DN) is a common microvascular complication of diabetes mellitus (DM), which can lead to renal failure in diabetic patients. At p......

JIF:4.332

Regulating the Imbalance of Gut Microbiota by Smilax china L. Polyphenols to Alleviate Dextran Sulfate Sodium-induced Inflammatory Bowel Diseases

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (2)

Smilax china L. is used not only as a kind of traditional Chinese herbal medicinal ingredients with various pharmacological properties, but also as fo......

JIF:4.332

Cordyceps Improves Obesity and its Related Inflammation via Modulation of Enterococcus cecorum Abundance and Bile Acid Metabolism

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (3)

Dysbiotic gut microbiota has been identified as a primary mediator of inherent inflammation that underlies the pathogenesis of obesity. Cordyceps comp......

JIF:4.332

The Leaves of Cyclocarya paliurus: A Functional Tea with Preventive and Therapeutic Potential of Type 2 Diabetes

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (6)

Type 2 diabetes mellitus (T2DM) has become a universal and chronic global public health concern and causes multiple complex complications. In order to......

JIF:4.332

A Systematic Review on Polysaccharides from Dendrobium Genus: Recent Advances in the Preparation, Structural Characterization, Bioactive Molecular Mechanisms, and Applications

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (2)

Dendrobium polysaccharides (DPSs) have aroused people's increasing attention in recent years as a result of their outstanding edible and medicinal val......

JIF:4.332

Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural Medicine

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (1)

The search for natural and efficacious antineoplastic drugs, with minimal toxicity and side effects, is an important part of antitumor drug research a......

JIF:4.332

Anticancer Effects of Taraxacum via Cell Cycle Arrest, Necrosis, Apoptosis, and Endoplasmic Reticulum Stress

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (2)

Dandelion (Taraxacum species) is a wild plant with over 2500 species. Flavonoids, phenolic compounds, saponins. sesquiterpenes, and sugars have been d......

JIF:4.332

Target-Specific Drug Discovery of Natural Products against SARS-CoV-2 Life Cycle and Cytokine Storm in COVID-19

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (4)

Coronavirus disease 2019 (COVID-19) is currently a worldwide pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currentl......

JIF:4.332

Efficacy and Safety of Chinese Medicine for COVID-19: A Systematic Review and Meta-Analysis

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (2)

This systematic review and meta-analysis aimed to evaluate the efficacy and safety of traditional Chinese medicine for COVID-19 treatment with a focus......

JIF:4.332

Mechanisms of Danggui Buxue Tang on Hematopoiesis via Multiple Targets and Multiple Components: Metabonomics Combined with Database Mining Technology

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (4)

This study aimed to explore the mechanism of action of Danggui Buxue Tang (DBT) with its multiple components and targets in the synergistic regulation......

JIF:4.332

Therapeutic Effect and Mechanism of Acupuncture in Autoimmune Diseases

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (3)

Autoimmune diseases (AIDs) are conditions arising from abnormal immune reactions to autoantigens, which can be defined as the loss of immune tolerance......

JIF:4.332

Protective Effects and Therapeutics of Ginsenosides for Improving Endothelial Dysfunction: From Therapeutic Potentials, Pharmaceutical Developments to Clinical Trials

期刊: AMERICAN JOURNAL OF CHINESE MEDICINE, 2022; 50 (3)

The endothelium covers the internal lumen of the entire circulatory system and plays an important modulatory role in vascular homeostasis. Endothelium......

JIF:4.332

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