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Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Endothelial progenitor cell (EPCs) proliferation decreased, accompanied by mitochondrial dysfunction and mitophagy impairment via the PINK1-PARK2 path......

JIF:5.489

Multiscale reconstruction of various vessels in the intact murine liver lobe

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

The liver contains a variety of vessels and participates in miscellaneous physiological functions. While past studies generally focused on certain hep......

JIF:5.489

A previous hemorrhagic stroke protects against a subsequent stroke via microglia alternative polarization

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Microglia in hemorrhagic stroke contribute to both acute-phase exacerbation and late-phase attenuation of injury. Here, by using the mouse model, we r......

JIF:5.489

Long non-coding RNA DARS-AS1 promotes tumor progression by directly suppressing PACT-mediated cellular stress

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Cancer cells evolve various mechanisms to overcome cellular stresses and maintain progression. Protein kinase R (PKR) and its protein activator (PACT)......

JIF:5.489

Analysis of genome and methylation changes in Chinese indigenous chickens over time provides insight into species conservation

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Comparisons of genomic and methylomic changes during the conservation of indigenous chicken breeds in China provide insight into conservation programm......

JIF:5.489

Enhancement of diatom growth and phytoplankton productivity with reduced O-2 availability is moderated by rising CO2

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Sun et al. investigate the effects of current ambient and potential future oxygen levels on phytoplankton growth and photosynthesis with field observa......

JIF:5.489

Precise control of embolic stroke with magnetized red blood cells in mice

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Precise embolism control in immature brains can facilitate mechanistic studies of brain damage and repair after perinatal arterial ischemic stroke (PA......

JIF:5.489

Cytosolic peptides encoding Ca(V)1 C-termini downregulate the calcium channel activity-neuritogenesis coupling

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

L-type Ca2+ (Ca(V)1) channels transduce channel activities into nuclear signals critical to neuritogenesis. Also, standalone peptides encoded by Ca(V)......

JIF:5.489

Otilonium bromide boosts antimicrobial activities of colistin against Gram-negative pathogens and their persisters

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

The drug otilonium bromide restores the activity of colistin against colistinresistant Gram-negative bacteria in vitro and in a mouse infection model,......

JIF:5.489

The evolution of conglobation in Ceratocanthinae

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Evolutionary and functional analyses alongside new fossil specimens expand our understanding of rolling-into-ball behaviour in pill scarab beetles. Co......

JIF:5.489

Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

The multiligand receptor RAGE (receptor for advanced glycation end-products) mediates phagocytosis in non-professional phagocytes (NPPs), for example ......

JIF:5.489

Metagenomic data from cerebrospinal fluid permits tracing the origin and spread of Neisseria meningitidis CC4821 in China

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Metagenomic next-generation sequencing (mNGS) is useful for difficult to cultivate pathogens. Here, we use cerebrospinal fluid mNGS to diagnose invasi......

JIF:5.489

Environment-specificity and universality of the microbial growth law

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

As the nutrient quality changes, the fractions of ribosomal proteins in the proteome are usually positively correlated with the growth rates due to th......

JIF:5.489

Efficient co-production of EPA and DHA by Schizochytrium sp. via regulation of the polyketide synthase pathway

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

Presently, the supply of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) traditionally produced by marine fisheries will be insufficient to......

JIF:5.489

TECRL deficiency results in aberrant mitochondrial function in cardiomyocytes

期刊: COMMUNICATIONS BIOLOGY, 2022; 5 (1)

The endoplasmic reticulum protein TECRL promotes mitochondrial function in cardiomyocytes and its knockout in mice leads to cardiac dysfunction, decre......

JIF:5.489

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