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Melatonin-related signaling pathways and their regulatory effects in aging organisms

期刊: BIOGERONTOLOGY, 2022; 23 (5)

Melatonin is a tryptophan-derived ancestral molecule evolved in bacteria. According to the endosymbiotic theory, eukaryotic cells received mitochondri......

JIF:3.743

Long-term dietary restriction ameliorates ageing-related renal fibrosis in male mice by normalizing mitochondrial functions and autophagy

期刊: BIOGERONTOLOGY, 2022; 23 (6)

As the kidneys age, gradual changes in the structures and functions of mitochondria occur. Dietary restriction (DR) can play a protective role in agei......

JIF:3.743

Immunogenicity of the BNT162b2 mRNA COVID-19 vaccine in older residents of a long-term care facility: relation with age, frailty and prior infection status

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Clinical and biological assessment of the COVID-19 vaccine efficacy in the frail population is of crucial importance. The study focuses on measuring t......

JIF:3.743

High stability of blood parameters during mouse lifespan: sex-specific effects of every-other-day fasting

期刊: BIOGERONTOLOGY, 2022; 23 (5)

Every-other-day fasting (EODF) is one type of caloric restriction that is proposed to have significant health benefits, including slowing aging-relate......

JIF:3.743

Contribution of senescent and reactive astrocytes on central nervous system inflammaging

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Astrocytes, the most predominant cells in the central nervous system (CNS), have well-recognized neuroprotective functions. However, during the CNS ag......

JIF:3.743

Geroscience: the need to address some issues

期刊: BIOGERONTOLOGY, 2022; 23 (1)

The geroscience field hypothesises that it could be possible to delay all age-related diseases by delaying the ageing process itself, and not by curin......

JIF:3.743

Mapping sex differences in the effects of protein and carbohydrates on lifespan and reproduction in Drosophila melanogaster: is measuring nutrient intake essential?

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Understanding how diet affects reproduction and survival is a central aim in evolutionary biology. Although this relationship is likely to differ betw......

JIF:3.743

Non-coding RNAs in photoaging-related mechanisms: a new paradigm in skin health

期刊: BIOGERONTOLOGY, 2022; 23 (3)

The aging of skin is a biological process affected by environmental or genetic factors. Exposure to ultraviolet (UV) radiation is the main environment......

JIF:3.743

Identification of Isthmin1 in the small annual fish, Nothobranchius guentheri, as a novel biomarker of aging and its potential rejuvenation activity

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Isthmin 1 (Ism1) has been shown to play roles in multiple biological processes including morphogenesis, hematopoiesis, antiviral immune response and s......

JIF:3.743

3-Bromopyruvate, a caloric restriction mimetic, exerts a mitohormetic effect to provide neuroprotection through activation of autophagy in rats during aging

期刊: BIOGERONTOLOGY, 2022; 23 (5)

In the present study, attempts have been made to evaluate the potential role of 3 Bromopyruvate (3-BP) a glycolytic inhibitor and a caloric restrictio......

JIF:3.743

Dietary intake of diosgenin delays aging of male fish Nothobranchius guentheri through modulation of multiple pathways that play prominent roles in ROS production

期刊: BIOGERONTOLOGY, 2022; 23 (2)

Oxidative stress including DNA damage, increased lipid and protein oxidation, is an important feature of aging. Diosgenin (DG) has been shown to have ......

JIF:3.743

G protein-coupled receptors that influence lifespan of human and animal models

期刊: BIOGERONTOLOGY, 2022; 23 (1)

Humanity has always sought to live longer and for this, multiple strategies have been tried with varying results. In this sense, G protein-coupled rec......

JIF:3.743

Correlative links between natural radiation and life expectancy in the US population

期刊: BIOGERONTOLOGY, 2022; 23 (4)

The linear no-threshold (LNT) hypothesis is still the ruling concept which dictates the radiation protection health policy and regulations. However, m......

JIF:3.743

Emerging cellular senescence-centric understanding of immunological aging and its potential modulation through dietary bioactive components

期刊: BIOGERONTOLOGY, 2022; 23 (6)

Immunological aging is strongly associated with the observable deleterious effects of human aging. Our understanding of the causes, effects, and thera......

JIF:3.743

Prematurely aging female mice improve their behavioural response, immunity, redox state, and lifespan after a short social interaction with non-prematurely aging mice

期刊: BIOGERONTOLOGY, 2022; 23 (3)

Adult prematurely aging mice (PAM), characterized by inadequate stress response, show premature immunosenescence and shorter lifespan compared to adul......

JIF:3.743

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