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Sorting nexin-4 regulates beta-amyloid production by modulating beta-site-activating cleavage enzyme-1
期刊： Alzheimers Research & Therapy, 2017; 9 ( )
Background: Amyloid precursor protein (APP) is cleaved by beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) to produce beta-amyloid (A bet......
Peripheral apoE isoform levels in cognitively normal APOE epsilon 3/epsilon 4 individuals are associated with regional gray matter volume and cerebral glucose metabolism
期刊： Alzheimers Research & Therapy, 2017; 9 ( )
Background: Carriers of the APOE epsilon 4 allele are at increased risk of developing Alzheimer's disease (AD), and have been shown to have reduced ce......
