期刊: ANNALS OF NEUROLOGY, 2021; 90 (3)
Objective Unidentified mechanisms largely restrict the viability of effective therapies in pharmacoresistant epilepsy. Our previous study revealed tha......
期刊: ANNALS OF NEUROLOGY, 2021; 89 (4)
The Mediator multiprotein complex functions as a regulator of RNA polymerase II-catalyzed gene transcription. In this study, exome sequencing detected......
Objective Understanding how different parts of the immune system contribute to pathogenesis in Parkinson's disease is a burning challenge with importa......
期刊: ANNALS OF NEUROLOGY, 2021; 89 (3)
Objective: Gut microbiome alterations in Parkinson disease (PD) have been reported repeatedly, but their functional relevance remains unclear. Fecal m......
期刊: ANNALS OF NEUROLOGY, 2020; 87 (3)
Objective Observational studies have indicated that life course adiposity is associated with amyotrophic lateral sclerosis (ALS). However, whether suc......
期刊: ANNALS OF NEUROLOGY, 2020; 88 (1)
Objective Dominant optic atrophy (DOA) is the most common inherited optic neuropathy, with a prevalence of 1:12,000 to 1:25,000. OPA1 mutations are fo......
期刊: ANNALS OF NEUROLOGY, 2020; 87 (3)
Objective Aging is a major risk factor for numerous neurological disorders, and the mechanisms underlying brain aging remain elusive. Recent animal st......
期刊: ANNALS OF NEUROLOGY, 2020; 87 (4)
Objective Observational epidemiological studies have reported a relationship between coffee intake and risk of stroke. However, evidence for this asso......
期刊: ANNALS OF NEUROLOGY, 2020; 88 (2)
Objective A hitherto undescribed phenotype of early onset muscular dystrophy associated with sensorineural hearing loss and primary ovarian insufficie......
期刊: ANNALS OF NEUROLOGY, 2020; 88 (2)
Objective The aim was to investigate whether intensive blood pressure treatment is associated with less hematoma growth and better outcome in intracer......
期刊: ANNALS OF NEUROLOGY, 2020; 88 (5)
Objective To determine whether priming with 1 or 25Hz repetitive transcranial magnetic stimulation (rTMS) will enhance the benefits from treadmill tra......