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Safety profile of the concomitant use of atorvastatin and cyclosporine in renal transplant recipients

期刊: PHARMAZIE, 2023; 78 (5)

Cyclosporine (CyA) and atorvastatin (AT) are often administered concomitantly to treat dyslipidemia in renal transplant recipients. However, CyA great......

Phenytoin's pharmacological interactions with medicinal herbs: a review

期刊: PHARMAZIE, 2023; 78 (6-7)

Physiologic changes due to aging, pregnancy, nutritional status, drug interactions, and can affect pharmacokinetics and pharmacodynamics of antiepilep......

Effect of sodium-glucose cotransporter-2 inhibitor administration on cardiac rehabilitation in patients with type 2 diabetes mellitus with heart failure

期刊: PHARMAZIE, 2023; 78 (6-7)

Cardiac rehabilitation in patients with diabetes mellitus and heart failure may be affected by anti-diabetic drugs. However, there are few reports on ......

Effect of baseline urinary glucose levels on the relationship between sodium-glucose cotransporter 2 inhibitors and serum uric acid in Japanese patients with type 2 diabetes mellitus

期刊: PHARMAZIE, 2023; 78 (11-12)

In patients with type 2 diabetes mellitus (T2DM), controlling serum uric acid (SUA) and blood glucose levels is important. Moreover, sodium -glucose c......

Anti-obesity effects of Hovenia dulcis branches in mouse adipocytes, 3T3-L1 cells, and high-fat diet obese mice

期刊: PHARMAZIE, 2023; 78 (6-7)

Hovenia dulcis has been reported to have various pharmacological activities, but most studies were done with its fruits. However, from an economic poi......

Development of LOX-1 antibody modified immuno-liposomes as drug carriers to macrophages in atherosclerotic lesions

期刊: PHARMAZIE, 2023; 78 (8)

We developed a drug delivery system for atherosclerotic lesions using immuno-liposomes. We focused on enhancing the delivery efficiency of the liposom......

Design and development of functionalized single-walled carbon nanotube-ethosomes for transdermal delivery of ketoprofen

期刊: PHARMAZIE, 2023; 78 (5)

The purpose of this study was to combine carbon nanotube with ethosomes in order to obtain hybrid nanocarriers for transdermal delivery of ketoprofen ......

Adverse drug event profile associated with anti-dementia drugs: analysis of a spontaneous reporting database

期刊: PHARMAZIE, 2023; 78 (5)

Adverse drug events (ADEs) rates associated with anti-dementia acetylcholinesterase inhibitors are estimated to be 5%-20% and show a wide range of sym......

Increased demand for pharmaceutical drugs containing potassium iodide in connection with the Russia-Ukraine conflict

期刊: PHARMAZIE, 2023; 78 (1-4)

The current conflict between Russia and Ukraine increased concerns in the German population of a release of radioactive substances, e.g. radioactive i......

Novel compounds with promising IDO1 inhibitory activity as new cancer drug candidates: Derivatives of N,N'-diphenylurea linked with 1,2,3-triazole

期刊: PHARMAZIE, 2023; 78 (1-4)

To explore potential indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors, we designed a series of compounds incorporating urea and 1,2,3-triazole structur......

Professor Georg Dragendorff (1836-1898) as a toxicologist

期刊: PHARMAZIE, 2023; 78 (8)

The professor of pharmacy, Johann Georg Noel Dragendorff (1836-1898) is primarily known in the history of pharmacy as a pharmacognosist and forensic c......

Efficacy of zinc acetate hydrate for hypozincemia in the elderly is influenced by the initial accumulated exposure dose after taking zinc acetate hydrate

期刊: PHARMAZIE, 2023; 78 (9-10)

This study aimed to determine the efficacy of zinc acetate hydrate (ZAH) for hypozincemia in elderly hospitalized patients with an accumulated exposur......

Effects of 5-fluorouracil co-administration on blood pressure in patients maintained on antihypertensives: a retrospective case series

期刊: PHARMAZIE, 2023; 78 (5)

This study aimed to investigate the possible drug-drug interactions (DDIs) of 5-FU with antihypertensives metab-olised by CYP3A4 and 2C9, using blood ......

Medication adherence of bisphosphonate weekly or monthly regimens in patients with osteoporosis using a nationwide large claims database

期刊: PHARMAZIE, 2023; 78 (9-10)

Bisphosphonate (BPN) therapy, which mainly targets osteoporosis, evolves rapidly, leaving patients and physicians with a substantial collection of BPN......

Delivery of free amino acids into and through the stratum corneum of the skin using micro emulsions and microemulsion-based hydrogels: Formulation, characterization, and ex-vivo permeation studies

期刊: PHARMAZIE, 2023; 78 (9-10)

Free amino acids constitute the largest portion (40%) of the natural moisturizing factor. Their level might decline and cause dry skin condition. The ......

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