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BSC2 enhances cell resistance to AmB by inhibiting oxidative damage in Saccharomyces cerevisiae

期刊: FREE RADICAL RESEARCH, 2020; 54 (4)

Amphotericin B has been the gold standard for the treatment of invasive mycosis for many years. Its resistance mechanisms are reported to be mainly re......

Edaravone attenuates myocyte apoptosis through the JAK2/STAT3 pathway in acute myocardial infarction

期刊: FREE RADICAL RESEARCH, 2020; 54 (5)

Basic and clinical studies have demonstrated that the free radical scavenger edaravone has cytoprotective effects on acute myocardial infarction (AMI)......

Silencing of long non-coding RNA LINC00520 promotes radiosensitivity of head and neck squamous cell carcinoma cells

期刊: FREE RADICAL RESEARCH, 2020; 54 (4)

Aberrant expression of LINC00520 has been identified in head and neck squamous carcinoma (HNSCC). However, its function in the radiosensitivity of HNS......

MicroRNA-326 prevents sepsis-induced acute lung injury via targeting TLR4

期刊: FREE RADICAL RESEARCH, 2020; 54 (6)

Unrestrained inflammation provokes oxidative stress and contributes to the development of sepsis-induced acute lung injury (ALI). MicroRNA-326 (miR-32......

Labile iron affects pharmacological ascorbate-induced toxicity in osteosarcoma cell lines

期刊: FREE RADICAL RESEARCH, 2020; 54 (6)

Vitamin C and iron are both important nutrients for humans and involved in several physiological processes. The biological activities of vitamin C and......

Coumestrol ameliorates doxorubicin-induced cardiotoxicity via activating AMPK alpha

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Doxorubicin (DOX) acts as the cornerstone in multiple tumour chemotherapy regimens, however, its clinical application is often impeded due to the indu......

Negative association between antioxidant vitamin intake and non-alcoholic fatty liver disease in Chinese non-diabetic adults: mediation models involving superoxide dismutase

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

We aimed to explore the association between antioxidant vitamin intake, oxidative stress related markers and non-alcoholic fatty liver disease (NAFLD)......

Up-regulation of LncRNA NEAT1 induces apoptosis of human placental trophoblasts

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

The trophoblast apoptosis induced by placental oxidative stress is a contributor to the pathological development of preeclampsia (PE), whereas the mol......

Study of the controversial resveratrol that interact with the endogenous glutathione thiyl radical in cancer cells

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Found in various natural food products, manyin vitroevidence indicated that resveratrol (RES) has been linked to neuroprotective and cardioprotective ......

Effects of GST null genotypes on individual susceptibility to atherosclerotic cardiovascular diseases: a meta-analysis

期刊: FREE RADICAL RESEARCH, 2020; 54 (8-9)

Some genetic association studies tried to investigate potential associations between glutathione S-transferase (GST) null genotypes and atheroscleroti......

Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis

期刊: FREE RADICAL RESEARCH, 2020; 54 (10)

Ischaemia-reperfusion injury (IRI) is closely related to cardiovascular disease (CVD), which is the leading cause of death and disability. Exosomes ap......

Knockdown of LINC00473 promotes radiosensitivity of non-small cell lung cancer cells via sponging miR-513a-3p

期刊: FREE RADICAL RESEARCH, 2020; 54 (10)

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. Radioresistance is a significant obstacle in NSCLC radiotherapy. Long non-c......

Persimmon oligomeric proanthocyanidins alleviate ultraviolet B-induced skin damage by regulating oxidative stress and inflammatory responses

期刊: FREE RADICAL RESEARCH, 2020; 54 (10)

Skin damage can be induced by excessive ultraviolet B (UV-B) irradiation. This study aimed to investigate the potential protective activity of persimm......

Metformin protects Escherichia coli from bleomycin-induced bactericide via enhanced generation of hydrogen peroxide

期刊: FREE RADICAL RESEARCH, 2020; 54 (1)

Bleomycin is a glycopeptide antibiotic that is widely employed in the therapy of a range of lymphomas and germ cell tumours. But the therapeutic effic......

Activation of STAT-3 signalling by RECK downregulation via ROS is involved in the 27-hydroxycholesterol-induced invasion in breast cancer cells

期刊: FREE RADICAL RESEARCH, 2020; 54 (2-3)

Breast cancer is an important and common tumour among women worldwide. We previously showed that 27-hydroxycholesterol (27HC) promoted the invasion an......

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