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SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1

期刊: ATHEROSCLEROSIS, 2022; 340 ()

Background and aims: Human vascular smooth muscle cells (HA-VSMCs) are an important cell type involved in atherosclerosis. Low density lipoprotein (LD......

JIF:3.704

Low shear stress inhibits endothelial mitophagy via caveolin-1/miR-7-5p/SQSTM1 signaling pathway

期刊: ATHEROSCLEROSIS, 2022; 356 ()

Background and aims: Mitophagy plays a crucial role in mitochondrial homeostasis and is closely associated with endothelial function. However, the mec......

JIF:3.704

Irisin alleviates vascular calcification by inhibiting VSMC osteoblastic transformation and mitochondria dysfunction via AMPK/Drp1 signaling pathway in chronic kidney disease

期刊: ATHEROSCLEROSIS, 2022; 346 ()

Background and aims: Vascular calcification (VC) is an intricate active process, significantly controlled by vascular smooth muscle cells (VSMCs). Mit......

JIF:3.704

The individual and joint associations of depression and sleep duration with cardiometabolic diseases and mortality: A prospective cohort study

期刊: ATHEROSCLEROSIS, 2022; 361 ()

Background and aims: Depression and sleep duration were only mutually adjusted in a few studies, and it is unknown whether these two factors are indep......

JIF:3.704

MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1

期刊: ATHEROSCLEROSIS, 2022; 348 ()

Background and aims: Cholesterol 7alpha-hydroxylase (CYP7A1) is the rate limiting enzyme of the bile acid biosynthetic pathway to convert cholesterol ......

JIF:3.704

Transcriptome analysis revealed a two-step transformation of vascular smooth muscle cells to macrophage-like cells

期刊: ATHEROSCLEROSIS, 2022; 346 ()

Background and aims: It is known that vascular smooth muscle cells (VSMCs) represent a major part of the atherosclerotic plaque. In addition to formin......

JIF:3.704

Ischemic risk in patients with heart failure with preserved ejection fraction: A post hoc analysis of the TOPCAT data

期刊: ATHEROSCLEROSIS, 2022; 344 ()

Background and aims: Heart failure with preserved ejection fraction (HFpEF) patients have a high burden of comorbidities that could predispose them to......

JIF:3.704

Global death burden and attributable risk factors of peripheral artery disease by age, sex, SDI regions, and countries from 1990 to 2030: Results from the Global Burden of Disease study 2019

期刊: ATHEROSCLEROSIS, 2022; 347 ()

Background and aims: Peripheral artery disease (PAD) is a prevalent cardiovascular disease. Understanding current and future disease burden of PAD and......

JIF:3.704

Blocking the NLRP3 inflammasome reduces osteogenic calcification and M1 macrophage polarization in a mouse model of calcified aortic valve stenosis

期刊: ATHEROSCLEROSIS, 2022; 347 ()

Background and aims: Activated innate immune cells infiltrating the valve and their secreted cytokines drive the differentiation of valve interstitial......

JIF:3.704

BMP-4 impedes endothelial cell migration in neointimal hyperplasia via FoXO-3 specific modulation of reactive oxygen species

期刊: ATHEROSCLEROSIS, 2022; 351 ()

Background and aims: Endothelial cell injury causes vascular barrier dysfunction and leukocyte recruitment to the underlying tissue. Bone morphogeneti......

JIF:3.704

Inhibition of S-adenosylhomocysteine hydrolase induces endothelial senescence via hTERT downregulation

期刊: ATHEROSCLEROSIS, 2022; 353 ()

Background and aims: It has been established that endothelial senescence plays a critical role in the development of atherosclerosis. Elevated S-adeno......

JIF:3.704

Bves maintains vascular smooth muscle cell contractile phenotype and protects against transplant vasculopathy via Dusp1-dependent p38MAPK and ERK1/2 signaling

期刊: ATHEROSCLEROSIS, 2022; 357 ()

Background and aims: Vascular smooth muscle cell (VSMC) plasticity is tightly associated with the pathological process of vasculopathy. Blood vessel e......

JIF:3.704

Impact of glycemic gap on 30-day adverse outcomes in patients with acute ST-segment elevation myocardial infarction

期刊: ATHEROSCLEROSIS, 2022; 360 ()

Background and aims: Stress-induced hyperglycemia (SIH) generally occurs in critical illness. Recently, glycemic gap (GAP) has been considered to be a......

JIF:3.704

Changes in adiposity modulate the APOA5 genetic effect on blood lipids: A longitudinal cohort study

期刊: ATHEROSCLEROSIS, 2022; 350 ()

Background and aims: The Apolipoprotein A5 (APOA5) rs662799 was significantly associated with blood lipid level at genome-wide significance level. Whe......

JIF:3.704

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