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JAK/STAT3 Signaling Activation Related to Distinct Clinicopathologic Features in Systemic ALK- Anaplastic Large Cell Lymphomas New Insights into Their Heterogeneity

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (1)

Systemic anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a group of heterogenous CD30(+) T-cell non-Hodgkin lymphom......

Sporadic and Familial Adenomatous Polyposis-associated Foveolar-type Adenoma of the Stomach

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (1)

Gastric foveolar-type adenoma (FA) is a rare benign neoplasm occurring either sporadically or in patients with familial adenomatous polyposis (FAP). H......

Sinonasal Amoebiasis An Unexpected Cause of Sinonasal Necroinflammatory Disease

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (1)

While amoebic infection is widely known as a cause of gastroenteritis, keratitis, and meningoencephalitis, amoebae are challenging to recognize at une......

Recurrent IDH2 Mutations in Salivary Gland Striated Duct Adenoma Define an Expanded Histologic Spectrum Distinct From Canalicular Adenoma

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (3)

Striated duct adenoma (SDA) is a rare salivary gland neoplasm defined by histologic similarity to normal striated ducts. However, doubt persists about......

The Distinctive Nature of Thyroid MALT Lymphomas Including IRTA1 Expression

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (3)

Mucosa-associated lymphoid tissue (MALT) lymphomas often express IgM and IRTA1 with only a minority demonstrating plasmacytic differentiation. However......

Mesothelioma In Situ Mimicking Well-differentiated Papillary Mesothelial Tumor

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (5)

We have previously hypothesized that well-differentiated papillary mesothelial tumor (WDPMT) consists of 2 morphologically identical lesions, one of w......

Unique Morphologic Findings in the Liver After Stereotactic Radiation for Cholangiocarcinoma

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (7)

Newer radiotherapy techniques, such as stereotactic body radiation, have been increasingly used as part of the treatment of cholangiocarcinomas, parti......

Genomic Analysis in the Categorization of Poorly Differentiated Primary Liver Carcinomas

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (11)

A subset of primary liver carcinomas (PLCs) cannot be classified as hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (iCCA) based on ......

Challenges in the Diagnosis of Epstein-Barr Virus-positive Inflammatory Follicular Dendritic Cell Sarcoma Extremely Wide Morphologic Spectrum and Immunophenotype

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (4)

Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell (FDC) sarcoma (EBV+ IFDCS) is a rare entity, and its histopathological charac......

Clinicopathologic Features of Severe Acute Hepatitis Associated With Adenovirus Infection in Children

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (9)

A recent increase in reports of severe acute hepatitis of unknown etiology in children is under investigation. Although adenovirus has been frequently......

Sweat Gland Tumors Arising on Acral Sites

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (10)

Recurrent oncogenic drivers have been identified in a variety of sweat gland tumors. Recently, integration of human papillomavirus type 42 (HPV42) has......

Comprehensive Clinical-Pathologic Assessment of Malignant Phyllodes Tumors

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (11)

The latest World Health Organization classification of breast tumors recommends diagnosing malignant phyllodes tumors (MPTs) when all 5 morphologic fe......

Head and Neck Mesenchymal Tumors with Kinase Fusions A Report of 15 Cases With Emphasis on Wide Anatomic Distribution and Diverse Histologic Appearance

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (2)

Mesenchymal tumors harboring various kinase fusions were recently recognized as emerging entities mainly in the soft tissues. We herein investigate th......

Recurrent EWSR1::COLCA2 Fusions Define a Novel Sarcoma With Spindle/Round Cell Morphology and Strong Predilection for the Sinonasal Tract

期刊: AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023; 47 (3)

The last 2 decades have attended a dynamic evolution in the nosology of poorly differentiated sinonasal tract malignancies, with several new molecular......

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